Btnl6 (butyrophilin-like 6) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Btnl6 (butyrophilin-like 6) Mus musculus
Analyze
No known orthologs.
Symbol: Btnl6
Name: butyrophilin-like 6
RGD ID: 1609618
MGI Page MGI
Description: Predicted to enable signaling receptor binding activity. Involved in extrathymic T cell selection. Predicted to be active in external side of plasma membrane.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: EG624681; Gm6519; NG1; NG13
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391734,726,844 - 34,737,750 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1734,726,778 - 34,736,326 (-)EnsemblGRCm39 Ensembl
GRCm381734,507,870 - 34,518,776 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1734,507,804 - 34,517,352 (-)EnsemblGRCm38mm10GRCm38
MGSCv371734,644,880 - 34,654,297 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361734,115,860 - 34,125,953 (-)NCBIMGSCv36mm8
Celera1737,602,952 - 37,612,369 (-)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1718.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
triptonide  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10803852   PMID:21873635   PMID:27528202   PMID:27641500   PMID:32724083  


Genomics

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:432
Count of miRNA genes:325
Interacting mature miRNAs:352
Transcripts:ENSMUST00000075483, ENSMUST00000173164
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10045977Tir9_mtrypanosome infection response 9 (mouse)Not determined172787811943885114Mouse
26884379Skwq5_mskull length QTL 5, 5 week (mouse)173311897454107028Mouse
1300890Bhr3_mbronchial hyperresponsiveness 3 (mouse)Not determined17397489048866091Mouse
11075105Modc1_mmodifier of Odc1 (mouse)172771579245622654Mouse
1300995Fembrs4_mfemur breaking strength 4 (mouse)Not determined171506165249061760Mouse
15039348Nmrs37_mNAFLD-associated magnetic resonance shift 37 (mouse)172781520961815209Mouse
4141357Mrdq1_mmodifier of retinal degeneration QTL 1 (mouse)Not determined3098790348039703Mouse
1302152Skull25_mskull morphology 25 (mouse)Not determined171681972150819843Mouse
1302028Asbb3_mautoimmune susceptibility in C57BL/6J and BALB/c 3 (mouse)Not determined171087811944878219Mouse
15039354Nmrs36_mNAFLD-associated magnetic resonance shift 36 (mouse)171914502553145025Mouse
4141215Mnic1_mmacronutrient intake, carbohydrate 1 (mouse)Not determined485475245670266Mouse
1300787Cd8mts5_mCD8 memory T cell subset 5 (mouse)Not determined17858491442585149Mouse
13524847Asrq8a_macoustic startle response 8a (mouse)171264696146646961Mouse
1300914Pcir4_mperiosteal circumference 4 (mouse)Not determined171506165249061760Mouse
13452396Leusq3_mleucocytosis susceptibility QTL 3 (mouse)171746220851462345Mouse
13452399Leusq6_mleucocytosis susceptibility QTL 6 (mouse)171746220851462345Mouse
1300535Char3_mP. chabaudi malaria resistance QTL 3 (mouse)Not determined171746220851462345Mouse
4140955Plgr1_mplague resistance locus 1 (mouse)Not determined3103350065033630Mouse
1302070Tbbmd7_mtotal body bone mineral density 7 (mouse)Not determined171506165249061760Mouse
10412214Sxbq3_mSGC/Knj cross B6 QTL 3 (mouse)Not determined171746220851462345Mouse
10412083Sm2_msusceptibility to Schistosoma mansoni infection 2 (mouse)Not determined171702994351030078Mouse
10412204Bbaa29_mB.burgdorferi-associated arthritis 29 (mouse)Not determined172605118560051352Mouse
10043949Pbft7_mpercent body fat 7 (mouse)Not determined17689393640893936Mouse
4141067Hbnr2_mHeligmosomoides bakeri nematode resistance 2 (mouse)Not determined1188597145886119Mouse
12904946Tammq8_mtibialis anterior muscle mass QTL 8 (mouse)171245178746451787Mouse
10412198Sst5_msusceptibility to tuberculosis 5 (mouse)Not determined172507658355712970Mouse
4142342Lfnq4_mlung function QTL 4 (mouse)Not determined1120648439364059Mouse
10412196Bbaa28_mB.burgdorferi-associated arthritis 28 (mouse)Not determined172558491443976235Mouse
1301935Skull24_mskull morphology 24 (mouse)Not determined17858491442585149Mouse
1302189Dps3_mdelta power in slow-wave sleep 3 (mouse)Not determined173381972136250180Mouse
1301331Lbw1_mlupus NZB x NZW 1 (mouse)Not determined171841835752420983Mouse
1301840Ssial4_msusceptibility to sialadenitiss 4 (mouse)Not determined171817541252178214Mouse
1300692Blmpf1_mbleomycin-induced pulmonary fibrosis 1 (mouse)Not determined173206165237644775Mouse
1357789Kdnw3_mkidney weight 3 (mouse)Not determined17485475247885665Mouse
1301338Lmr1_mleishmaniasis resistance 1 (mouse)Not determined171008134086996400Mouse
1300703Uvbi2_mUVB induced immunosuppression 2 (mouse)Not determined172862240662622654Mouse
11038694Pas19_mpulmonary adenoma susceptibility 19 (mouse)172971116434754437Mouse
1301056Pas2_mpulmonary adenoma susceptibility 2 (mouse)Not determined171842214152424327Mouse
1301454Eae5_msusceptibility to experimental allergic encephalomyelitis 5 (mouse)Not determined172461275058612864Mouse
14747010Mancz14_mmandible centroid size 14 (mouse)171199818445998184Mouse
1302005Loco2_mlocomotor activity 2 (mouse)Not determined172688497260885114Mouse
4141272Tfv1_mtotal food volume 1 (mouse)Not determined485475265637357Mouse
1300602Eye2_meye weight 2 (mouse)Not determined172650533741105037Mouse
25394538Skmw84_mskeletal muscle weight 84, TA (mouse)173266042635520036Mouse
10412276Leci2_mleukocyte endothelial cell interactions 2 (mouse)Not determined17334817537348299Mouse
1301759Sles1_msystemic lupus erythmatosus suppressor 1 (mouse)Not determined173421989035175937Mouse
1302140Wta4_mweight adult 4 (mouse)Not determined171681972150819843Mouse
1300706Alan1_malloantigen response 1 (mouse)Not determined17485475246469702Mouse
1558886Lgth9_mbody length 9 (mouse)Not determined171506165249061760Mouse
1558758Kcal2_mkilocalorie 2 (mouse)Not determined172640101252911704Mouse
4142150Stheal11_msoft tissue heal 11 (mouse)Not determined171228621183361768Mouse
11081168Tir7_mtrypanosome infection response 7 (mouse)171412337248123496Mouse
1300589Myaa2_mmodifier of Yaa 2 (mouse)Not determined173013255564132666Mouse


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000075483   ⟹   ENSMUSP00000074927
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1734,726,909 - 34,736,326 (-)Ensembl
GRCm38.p6 Ensembl1734,507,935 - 34,517,352 (-)Ensembl
Ensembl Acc Id: ENSMUST00000173164
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1734,726,778 - 34,736,326 (-)Ensembl
GRCm38.p6 Ensembl1734,507,804 - 34,517,352 (-)Ensembl
RefSeq Acc Id: NM_030747   ⟹   NP_109672
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391734,726,909 - 34,736,326 (-)NCBI
GRCm381734,507,935 - 34,517,352 (-)ENTREZGENE
MGSCv371734,644,880 - 34,654,297 (-)RGD
Celera1737,602,952 - 37,612,369 (-)RGD
cM Map17 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_030249938   ⟹   XP_030105798
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391734,726,844 - 34,737,750 (-)NCBI
GRCm381734,507,870 - 34,518,776 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_109672 (Get FASTA)   NCBI Sequence Viewer  
  XP_030105798 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAC05291 (Get FASTA)   NCBI Sequence Viewer  
  CAM18608 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000074927
  ENSMUSP00000074927.5
RefSeq Acc Id: NP_109672   ⟸   NM_030747
- Peptide Label: precursor
- UniProtKB: A2CG22 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_030105798   ⟸   XM_030249938
- Peptide Label: isoform X1
- UniProtKB: A2CG22 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSMUSP00000074927   ⟸   ENSMUST00000075483
Protein Domains
B30.2/SPRY   Ig-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A2CG22-F1-model_v2 AlphaFold A2CG22 1-539 view protein structure

Promoters
RGD ID:13675702
Promoter ID:EPDNEW_M22000
Type:single initiation site
Name:Btnl6_1
Description:Mus musculus butyrophilin-like 6 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381734,517,365 - 34,517,425EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1932038 AgrOrtholog
Ensembl Genes ENSMUSG00000092618 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000075483 ENTREZGENE
  ENSMUST00000075483.5 UniProtKB/TrEMBL
Gene3D-CATH 2.60.120.920 UniProtKB/TrEMBL
  2.60.40.10 UniProtKB/TrEMBL
InterPro B30.2/SPRY UniProtKB/TrEMBL
  B30.2/SPRY_sf UniProtKB/TrEMBL
  BTN3A2-like_Ig-C UniProtKB/TrEMBL
  Butyrophylin UniProtKB/TrEMBL
  ConA-like_dom UniProtKB/TrEMBL
  Ig-like UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  Ig_V-set UniProtKB/TrEMBL
  IgSF_BTN/MOG UniProtKB/TrEMBL
  SPRY_rcpt UniProtKB/TrEMBL
KEGG Report mmu:624681 UniProtKB/TrEMBL
MGD MGI:1932038 ENTREZGENE
NCBI Gene Btnl6 ENTREZGENE
PANTHER BUTYROPHILIN UniProtKB/TrEMBL
  BUTYROPHILIN, SUBFAMILY 3, MEMBER A3-RELATED UniProtKB/TrEMBL
Pfam C2-set_3 UniProtKB/TrEMBL
  SPRY UniProtKB/TrEMBL
  V-set UniProtKB/TrEMBL
PhenoGen Btnl6 PhenoGen
PRINTS BUTYPHLNCDUF UniProtKB/TrEMBL
PROSITE B302_SPRY UniProtKB/TrEMBL
  IG_LIKE UniProtKB/TrEMBL
SMART SM00409 UniProtKB/TrEMBL
  SPRY UniProtKB/TrEMBL
Superfamily-SCOP ConA_like_lec_gl UniProtKB/TrEMBL
  SSF48726 UniProtKB/TrEMBL
UniProt A2CG22 ENTREZGENE, UniProtKB/TrEMBL