LIMD2 (LIM domain containing 2) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: LIMD2 (LIM domain containing 2) Homo sapiens
Analyze
Symbol: LIMD2
Name: LIM domain containing 2
RGD ID: 1603297
HGNC Page HGNC:28142
Description: Predicted to enable actin filament binding activity. Predicted to be involved in actin filament bundle assembly. Located in cytosol and nucleoplasm.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LIM domain-containing protein 2; MGC10986; testicular tissue protein Li 106
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381763,695,888 - 63,701,155 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1763,695,888 - 63,701,172 (-)EnsemblGRCh38hg38GRCh38
GRCh371761,773,248 - 61,777,485 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361759,126,981 - 59,131,251 (-)NCBINCBI36Build 36hg18NCBI36
Celera1756,161,369 - 56,165,639 (-)NCBICelera
Cytogenetic Map17q23.3NCBI
HuRef1757,141,395 - 57,145,601 (-)NCBIHuRef
CHM1_11761,837,661 - 61,841,931 (-)NCBICHM1_1
T2T-CHM13v2.01764,566,794 - 64,571,430 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:14702039   PMID:15203218   PMID:15489334   PMID:16712791   PMID:16751776   PMID:21873635   PMID:24590809   PMID:25416956   PMID:28378594   PMID:29560564   PMID:30196744  
PMID:30221696   PMID:31586073   PMID:33111431   PMID:34189442   PMID:34724866   PMID:35182466   PMID:35563538   PMID:37936458  


Genomics

Comparative Map Data
LIMD2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381763,695,888 - 63,701,155 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1763,695,888 - 63,701,172 (-)EnsemblGRCh38hg38GRCh38
GRCh371761,773,248 - 61,777,485 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361759,126,981 - 59,131,251 (-)NCBINCBI36Build 36hg18NCBI36
Celera1756,161,369 - 56,165,639 (-)NCBICelera
Cytogenetic Map17q23.3NCBI
HuRef1757,141,395 - 57,145,601 (-)NCBIHuRef
CHM1_11761,837,661 - 61,841,931 (-)NCBICHM1_1
T2T-CHM13v2.01764,566,794 - 64,571,430 (-)NCBIT2T-CHM13v2.0
Limd2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911106,047,080 - 106,051,555 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11106,047,082 - 106,051,686 (-)EnsemblGRCm39 Ensembl
GRCm3811106,156,254 - 106,160,729 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11106,156,256 - 106,160,860 (-)EnsemblGRCm38mm10GRCm38
MGSCv3711106,017,570 - 106,021,456 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611105,972,346 - 105,976,232 (-)NCBIMGSCv36mm8
Celera11117,886,474 - 117,890,360 (-)NCBICelera
Cytogenetic Map11E1NCBI
cM Map1168.89NCBI
Limd2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81091,590,079 - 91,592,747 (-)NCBIGRCr8
mRatBN7.21091,090,279 - 91,092,772 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1091,090,280 - 91,092,775 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1096,144,910 - 96,146,990 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01095,608,080 - 95,610,160 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01091,018,839 - 91,020,919 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01094,350,789 - 94,353,301 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1094,350,817 - 94,352,880 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01094,099,457 - 94,101,947 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41095,552,509 - 95,554,534 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11095,566,878 - 95,568,904 (-)NCBI
Celera1089,766,367 - 89,768,394 (-)NCBICelera
Cytogenetic Map10q32.1NCBI
Limd2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554788,120,156 - 8,121,826 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554788,120,405 - 8,121,826 (+)NCBIChiLan1.0ChiLan1.0
LIMD2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21979,870,010 - 79,873,296 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11784,687,464 - 84,690,750 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01757,778,107 - 57,781,401 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11762,924,378 - 62,926,236 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1762,924,378 - 62,926,236 (-)Ensemblpanpan1.1panPan2
LIMD2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1911,679,963 - 11,682,389 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl911,680,617 - 11,681,655 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha912,639,911 - 12,642,358 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0913,340,702 - 13,343,148 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl913,340,711 - 13,343,125 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1912,287,794 - 12,290,238 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0915,241,953 - 15,244,389 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0915,244,813 - 15,247,278 (+)NCBIUU_Cfam_GSD_1.0
Limd2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560214,845,157 - 14,847,961 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365414,346,644 - 4,348,120 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365414,346,633 - 4,348,367 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LIMD2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1215,222,973 - 15,227,700 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11215,223,798 - 15,229,634 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21215,212,872 - 15,214,392 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LIMD2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11657,588,067 - 57,593,032 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1657,590,699 - 57,592,469 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607728,201,352 - 28,204,052 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Limd2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248491,187,599 - 1,189,441 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248491,186,946 - 1,190,059 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in LIMD2
5 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 17q21.33-24.2(chr17:36449220-68170214)x3 copy number gain See cases [RCV000050957] Chr17:36449220..68170214 [GRCh38]
Chr17:48563237..65936105 [GRCh37]
Chr17:45918236..63677950 [NCBI36]
Chr17:17q21.33-24.2		 pathogenic
GRCh38/hg38 17q23.2-25.3(chr17:36449220-83086677)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052483]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052483]|See cases [RCV000052483] Chr17:36449220..83086677 [GRCh38]
Chr17:58617905..81044553 [GRCh37]
Chr17:55972687..78637842 [NCBI36]
Chr17:17q23.2-25.3		 pathogenic
GRCh37/hg19 17q23-24(chr17:59209629-64222315)x3 copy number gain See cases [RCV000052485] Chr17:59209629..64222315 [GRCh37]
Chr17:56564411..61652777 [NCBI36]
Chr17:17q23-24		 pathogenic
GRCh38/hg38 17q23.1-25.1(chr17:36449220-75053130)x3 copy number gain See cases [RCV000137437] Chr17:36449220..75053130 [GRCh38]
Chr17:57595736..73049225 [GRCh37]
Chr17:54950518..70560820 [NCBI36]
Chr17:17q23.1-25.1		 pathogenic
GRCh38/hg38 17q23.3(chr17:63648253-63855879)x3 copy number gain See cases [RCV000139605] Chr17:63648253..63855879 [GRCh38]
Chr17:61725613..61933239 [GRCh37]
Chr17:59079345..59286971 [NCBI36]
Chr17:17q23.3		 uncertain significance
GRCh37/hg19 17q22-23.3(chr17:56321134-62080001)x3 copy number gain See cases [RCV000240364] Chr17:56321134..62080001 [GRCh37]
Chr17:17q22-23.3		 pathogenic
NM_030576.4(LIMD2):c.61A>G (p.Ser21Gly) single nucleotide variant not specified [RCV004288021] Chr17:63699051 [GRCh38]
Chr17:61776411 [GRCh37]
Chr17:17q23.3		 uncertain significance
GRCh37/hg19 17q21.31-25.3(chr17:42580684-81085615)x3 copy number gain See cases [RCV000447823] Chr17:42580684..81085615 [GRCh37]
Chr17:17q21.31-25.3		 pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:526-81041938) copy number gain See cases [RCV000511439] Chr17:526..81041938 [GRCh37]
Chr17:17p13.3-q25.3		 pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:526-81041938)x3 copy number gain See cases [RCV000512441] Chr17:526..81041938 [GRCh37]
Chr17:17p13.3-q25.3		 pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:8547-81060040)x3 copy number gain not provided [RCV000739324] Chr17:8547..81060040 [GRCh37]
Chr17:17p13.3-q25.3		 pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:7214-81058310)x3 copy number gain not provided [RCV000739320] Chr17:7214..81058310 [GRCh37]
Chr17:17p13.3-q25.3		 pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:12344-81057996)x3 copy number gain not provided [RCV000739325] Chr17:12344..81057996 [GRCh37]
Chr17:17p13.3-q25.3		 pathogenic
GRCh37/hg19 17q23.2-24.2(chr17:59597348-64886364)x3 copy number gain not provided [RCV000752158] Chr17:59597348..64886364 [GRCh37]
Chr17:17q23.2-24.2		 pathogenic
GRCh37/hg19 17q22-24.2(chr17:57357088-66306668) copy number gain not provided [RCV000767764] Chr17:57357088..66306668 [GRCh37]
Chr17:17q22-24.2		 pathogenic
GRCh37/hg19 17q23.1-24.2(chr17:57869604-67078443)x3 copy number gain not provided [RCV000845965] Chr17:57869604..67078443 [GRCh37]
Chr17:17q23.1-24.2		 pathogenic
NM_030576.4(LIMD2):c.359T>C (p.Val120Ala) single nucleotide variant not specified [RCV004098782] Chr17:63698577 [GRCh38]
Chr17:61775937 [GRCh37]
Chr17:17q23.3		 uncertain significance
NM_030576.4(LIMD2):c.41A>G (p.His14Arg) single nucleotide variant not specified [RCV004239176] Chr17:63699258 [GRCh38]
Chr17:61776618 [GRCh37]
Chr17:17q23.3		 uncertain significance
NM_030576.4(LIMD2):c.101C>A (p.Ala34Asp) single nucleotide variant not specified [RCV004221754] Chr17:63698922 [GRCh38]
Chr17:61776282 [GRCh37]
Chr17:17q23.3		 uncertain significance
GRCh37/hg19 17q23.2-23.3(chr17:58596397-62540700)x3 copy number gain See cases [RCV004442795] Chr17:58596397..62540700 [GRCh37]
Chr17:17q23.2-23.3		 uncertain significance
NM_030576.4(LIMD2):c.179T>C (p.Phe60Ser) single nucleotide variant not specified [RCV004415243] Chr17:63698844 [GRCh38]
Chr17:61776204 [GRCh37]
Chr17:17q23.3		 uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:8069
Count of miRNA genes:1108
Interacting mature miRNAs:1428
Transcripts:ENST00000259006, ENST00000578061, ENST00000578067, ENST00000578297, ENST00000578402, ENST00000578993, ENST00000579329, ENST00000579814, ENST00000580222, ENST00000582055, ENST00000583211, ENST00000584645
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
WI-11047  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371761,773,389 - 61,773,580UniSTSGRCh37
Build 361759,127,121 - 59,127,312RGDNCBI36
Celera1756,161,509 - 56,161,700RGD
Cytogenetic Map17q23.3UniSTS
HuRef1757,141,535 - 57,141,726UniSTS
GeneMap99-GB4 RH Map17402.7UniSTS
Whitehead-RH Map17461.0UniSTS


Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
pharyngeal arch
renal system
reproductive system
respiratory system
sensory system
visual system
1204 2437 2788 2253 4974 1726 2350 6 624 1951 465 2270 7304 6471 53 3734 1 852 1744 1616 174 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_030576 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005257703 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005257705 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006722124 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047436853 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054317422 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054317423 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054317424 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AA251318 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC046185 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK092301 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK307353 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK310718 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY037154 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC004400 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC025738 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC051812 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB148563 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CD632650 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471109 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068261 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ592947 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM005419 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENST00000259006   ⟹   ENSP00000259006
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1763,695,888 - 63,700,125 (-)Ensembl
Ensembl Acc Id: ENST00000578061   ⟹   ENSP00000464003
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1763,698,289 - 63,699,861 (-)Ensembl
Ensembl Acc Id: ENST00000578067
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1763,697,816 - 63,700,108 (-)Ensembl
Ensembl Acc Id: ENST00000578297
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1763,698,498 - 63,699,344 (-)Ensembl
Ensembl Acc Id: ENST00000578402   ⟹   ENSP00000462707
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1763,697,816 - 63,700,685 (-)Ensembl
Ensembl Acc Id: ENST00000578993   ⟹   ENSP00000462125
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1763,698,335 - 63,700,102 (-)Ensembl
Ensembl Acc Id: ENST00000579329
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1763,698,256 - 63,699,362 (-)Ensembl
Ensembl Acc Id: ENST00000579814
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1763,698,467 - 63,700,132 (-)Ensembl
Ensembl Acc Id: ENST00000580222   ⟹   ENSP00000463409
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1763,698,189 - 63,700,113 (-)Ensembl
Ensembl Acc Id: ENST00000582055   ⟹   ENSP00000463656
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1763,698,478 - 63,699,162 (-)Ensembl
Ensembl Acc Id: ENST00000583211   ⟹   ENSP00000463089
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1763,697,833 - 63,700,132 (-)Ensembl
Ensembl Acc Id: ENST00000584645   ⟹   ENSP00000463805
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1763,698,609 - 63,701,172 (-)Ensembl
RefSeq Acc Id: NM_030576   ⟹   NP_085053
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381763,695,888 - 63,700,125 (-)NCBI
GRCh371761,773,249 - 61,778,527 (-)NCBI
Build 361759,126,981 - 59,131,251 (-)NCBI Archive
Celera1756,161,369 - 56,165,639 (-)RGD
HuRef1757,141,395 - 57,145,601 (-)ENTREZGENE
CHM1_11761,837,661 - 61,841,931 (-)NCBI
T2T-CHM13v2.01764,566,794 - 64,571,030 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005257703   ⟹   XP_005257760
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381763,695,888 - 63,700,125 (-)NCBI
GRCh371761,773,249 - 61,778,527 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005257705   ⟹   XP_005257762
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381763,695,888 - 63,701,155 (-)NCBI
GRCh371761,773,249 - 61,778,527 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006722124   ⟹   XP_006722187
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381763,695,888 - 63,700,125 (-)NCBI
Sequence:
RefSeq Acc Id: XM_047436853   ⟹   XP_047292809
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381763,695,888 - 63,700,525 (-)NCBI
RefSeq Acc Id: XM_054317422   ⟹   XP_054173397
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01764,566,794 - 64,571,024 (-)NCBI
RefSeq Acc Id: XM_054317423   ⟹   XP_054173398
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01764,566,794 - 64,570,907 (-)NCBI
RefSeq Acc Id: XM_054317424   ⟹   XP_054173399
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01764,566,794 - 64,571,430 (-)NCBI
RefSeq Acc Id: NP_085053   ⟸   NM_030576
- UniProtKB: D3DU16 (UniProtKB/Swiss-Prot),   Q96S91 (UniProtKB/Swiss-Prot),   Q9BT23 (UniProtKB/Swiss-Prot),   A0A140VJN0 (UniProtKB/TrEMBL),   J3QQM5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005257760   ⟸   XM_005257703
- Peptide Label: isoform X1
- UniProtKB: D3DU16 (UniProtKB/Swiss-Prot),   Q96S91 (UniProtKB/Swiss-Prot),   Q9BT23 (UniProtKB/Swiss-Prot),   A0A140VJN0 (UniProtKB/TrEMBL),   J3QQM5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005257762   ⟸   XM_005257705
- Peptide Label: isoform X1
- UniProtKB: D3DU16 (UniProtKB/Swiss-Prot),   Q96S91 (UniProtKB/Swiss-Prot),   Q9BT23 (UniProtKB/Swiss-Prot),   A0A140VJN0 (UniProtKB/TrEMBL),   J3QQM5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006722187   ⟸   XM_006722124
- Peptide Label: isoform X1
- UniProtKB: D3DU16 (UniProtKB/Swiss-Prot),   Q96S91 (UniProtKB/Swiss-Prot),   Q9BT23 (UniProtKB/Swiss-Prot),   A0A140VJN0 (UniProtKB/TrEMBL),   J3QQM5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSP00000463409   ⟸   ENST00000580222
Ensembl Acc Id: ENSP00000463656   ⟸   ENST00000582055
Ensembl Acc Id: ENSP00000463089   ⟸   ENST00000583211
Ensembl Acc Id: ENSP00000463805   ⟸   ENST00000584645
Ensembl Acc Id: ENSP00000259006   ⟸   ENST00000259006
Ensembl Acc Id: ENSP00000462707   ⟸   ENST00000578402
Ensembl Acc Id: ENSP00000462125   ⟸   ENST00000578993
Ensembl Acc Id: ENSP00000464003   ⟸   ENST00000578061
RefSeq Acc Id: XP_047292809   ⟸   XM_047436853
- Peptide Label: isoform X1
- UniProtKB: Q9BT23 (UniProtKB/Swiss-Prot),   D3DU16 (UniProtKB/Swiss-Prot),   Q96S91 (UniProtKB/Swiss-Prot),   A0A140VJN0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054173399   ⟸   XM_054317424
- Peptide Label: isoform X1
- UniProtKB: Q9BT23 (UniProtKB/Swiss-Prot),   D3DU16 (UniProtKB/Swiss-Prot),   Q96S91 (UniProtKB/Swiss-Prot),   A0A140VJN0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054173397   ⟸   XM_054317422
- Peptide Label: isoform X1
- UniProtKB: Q9BT23 (UniProtKB/Swiss-Prot),   D3DU16 (UniProtKB/Swiss-Prot),   Q96S91 (UniProtKB/Swiss-Prot),   A0A140VJN0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054173398   ⟸   XM_054317423
- Peptide Label: isoform X1
- UniProtKB: Q9BT23 (UniProtKB/Swiss-Prot),   D3DU16 (UniProtKB/Swiss-Prot),   Q96S91 (UniProtKB/Swiss-Prot),   A0A140VJN0 (UniProtKB/TrEMBL)
Protein Domains
LIM zinc-binding

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9BT23-F1-model_v2 AlphaFold Q9BT23 1-127 view protein structure

Promoters
RGD ID:6794275
Promoter ID:HG_KWN:26827
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   K562,   Lymphoblastoid,   NB4
Transcripts:NM_030576,   UC002JBK.2,   UC002JBL.2
Position:
Human AssemblyChrPosition (strand)Source
Build 361759,131,136 - 59,132,367 (-)MPROMDB
RGD ID:7235961
Promoter ID:EPDNEW_H23727
Type:initiation region
Name:LIMD2_2
Description:LIM domain containing 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H23728  EPDNEW_H23729  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381763,699,363 - 63,699,423EPDNEW
RGD ID:7235963
Promoter ID:EPDNEW_H23728
Type:initiation region
Name:LIMD2_1
Description:LIM domain containing 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H23727  EPDNEW_H23729  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381763,700,125 - 63,700,185EPDNEW
RGD ID:7235965
Promoter ID:EPDNEW_H23729
Type:initiation region
Name:LIMD2_3
Description:LIM domain containing 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H23727  EPDNEW_H23728  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381763,701,155 - 63,701,215EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:28142 AgrOrtholog
COSMIC LIMD2 COSMIC
Ensembl Genes ENSG00000136490 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000259006 ENTREZGENE
  ENST00000259006.8 UniProtKB/Swiss-Prot
  ENST00000578061 ENTREZGENE
  ENST00000578061.5 UniProtKB/Swiss-Prot
  ENST00000578402 ENTREZGENE
  ENST00000578402.5 UniProtKB/Swiss-Prot
  ENST00000578993.5 UniProtKB/TrEMBL
  ENST00000580222.5 UniProtKB/TrEMBL
  ENST00000582055.1 UniProtKB/TrEMBL
  ENST00000583211.5 UniProtKB/TrEMBL
  ENST00000584645 ENTREZGENE
  ENST00000584645.1 UniProtKB/TrEMBL
Gene3D-CATH Cysteine Rich Protein UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000136490 GTEx
HGNC ID HGNC:28142 ENTREZGENE
Human Proteome Map LIMD2 Human Proteome Map
InterPro LIM_LIMD2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_LIM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:80774 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 80774 ENTREZGENE
PANTHER LIM ZINC-BINDING DOMAIN-CONTAINING PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  OS06G0237300 PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam LIM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA143485528 PharmGKB
PROSITE LIM_DOMAIN_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LIM_DOMAIN_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART LIM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Glucocorticoid receptor-like (DNA-binding domain) UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A140VJN0 ENTREZGENE, UniProtKB/TrEMBL
  D3DU16 ENTREZGENE
  J3KRR0_HUMAN UniProtKB/TrEMBL
  J3QL69_HUMAN UniProtKB/TrEMBL
  J3QQM5 ENTREZGENE, UniProtKB/TrEMBL
  LIMD2_HUMAN UniProtKB/Swiss-Prot
  Q96S91 ENTREZGENE
  Q9BT23 ENTREZGENE
UniProt Secondary D3DU16 UniProtKB/Swiss-Prot
  Q96S91 UniProtKB/Swiss-Prot