SNORA81 (small nucleolar RNA, H/ACA box 81) - Rat Genome Database

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Gene: SNORA81 (small nucleolar RNA, H/ACA box 81) Homo sapiens
Analyze
Symbol: SNORA81
Name: small nucleolar RNA, H/ACA box 81
RGD ID: 1602550
HGNC Page HGNC:32667
Description: Predicted to be involved in RNA processing. Predicted to be located in nucleolus.
Type: snorna
RefSeq Status: VALIDATED
Previously known as: HBI-61
RGD Orthologs
Mouse
Rat
Dog
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383186,786,676 - 186,786,852 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3186,786,675 - 186,786,852 (+)EnsemblGRCh38hg38GRCh38
GRCh373186,504,465 - 186,504,641 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363187,987,158 - 187,987,335 (+)NCBINCBI36Build 36hg18NCBI36
Celera3184,940,626 - 184,940,803 (+)NCBICelera
Cytogenetic Map3q27.3NCBI
HuRef3183,914,141 - 183,914,318 (+)NCBIHuRef
CHM1_13186,468,041 - 186,468,218 (+)NCBICHM1_1
T2T-CHM13v2.03189,608,706 - 189,608,882 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
3MC syndrome 1  (IAGP)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleolus  (IEA)

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:15199136   PMID:16361266   PMID:16381836   PMID:19446021   PMID:30165668  


Genomics

Comparative Map Data
SNORA81
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383186,786,676 - 186,786,852 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3186,786,675 - 186,786,852 (+)EnsemblGRCh38hg38GRCh38
GRCh373186,504,465 - 186,504,641 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363187,987,158 - 187,987,335 (+)NCBINCBI36Build 36hg18NCBI36
Celera3184,940,626 - 184,940,803 (+)NCBICelera
Cytogenetic Map3q27.3NCBI
HuRef3183,914,141 - 183,914,318 (+)NCBIHuRef
CHM1_13186,468,041 - 186,468,218 (+)NCBICHM1_1
T2T-CHM13v2.03189,608,706 - 189,608,882 (+)NCBIT2T-CHM13v2.0
Snora81
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391622,929,520 - 22,929,683 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1622,929,503 - 22,929,608 (+)EnsemblGRCm39 Ensembl
GRCm39 Ensembl1622,929,506 - 22,929,683 (+)EnsemblGRCm39 Ensembl
GRCm381623,110,770 - 23,110,933 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1623,110,756 - 23,110,933 (+)EnsemblGRCm38mm10GRCm38
Cytogenetic Map16B1NCBI
cM Map1613.93NCBI
Snora81
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81028,278,802 - 28,278,949 (+)NCBIGRCr8
mRatBN7.21177,767,579 - 77,767,756 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1027,777,322 - 27,777,469 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0 Ensembl1181,376,500 - 81,376,677 (-)NCBIRnor6.0rn6Rnor6.0
Cytogenetic Map11q23NCBI
LOC119867578
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Dog10K_Boxer_Tasha3423,443,458 - 23,443,633 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03419,269,499 - 19,269,674 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.13419,300,649 - 19,300,824 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03419,300,652 - 19,300,827 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03419,528,525 - 19,528,700 (+)NCBIUU_Cfam_GSD_1.0


Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 3q26.33-28(chr3:182678453-188418928)x1 copy number loss See cases [RCV000051607] Chr3:182678453..188418928 [GRCh38]
Chr3:182396241..188136716 [GRCh37]
Chr3:183878935..189619410 [NCBI36]
Chr3:3q26.33-28
pathogenic
GRCh38/hg38 3q27.2-29(chr3:185485849-198110178)x1 copy number loss See cases [RCV000051608] Chr3:185485849..198110178 [GRCh38]
Chr3:185203637..197837049 [GRCh37]
Chr3:186686331..199321446 [NCBI36]
Chr3:3q27.2-29
pathogenic
GRCh38/hg38 3q27.2-28(chr3:186204253-192214251)x1 copy number loss See cases [RCV000051609] Chr3:186204253..192214251 [GRCh38]
Chr3:185922042..191932040 [GRCh37]
Chr3:187404736..193414734 [NCBI36]
Chr3:3q27.2-28
pathogenic
GRCh38/hg38 3q22.3-29(chr3:137126982-198110178)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051723]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051723]|See cases [RCV000051723] Chr3:137126982..198110178 [GRCh38]
Chr3:136845824..197837049 [GRCh37]
Chr3:138328514..199321446 [NCBI36]
Chr3:3q22.3-29
pathogenic
GRCh38/hg38 3q24-29(chr3:147521892-198096565)x3 copy number gain See cases [RCV000051725] Chr3:147521892..198096565 [GRCh38]
Chr3:147239679..197823436 [GRCh37]
Chr3:148722369..199307833 [NCBI36]
Chr3:3q24-29
pathogenic
GRCh38/hg38 3q25.31-29(chr3:157293378-198134727)x3 copy number gain See cases [RCV000051726] Chr3:157293378..198134727 [GRCh38]
Chr3:157011167..197861598 [GRCh37]
Chr3:158493861..199345995 [NCBI36]
Chr3:3q25.31-29
pathogenic
GRCh38/hg38 3q26.32-29(chr3:178411707-198110319)x3 copy number gain See cases [RCV000051736] Chr3:178411707..198110319 [GRCh38]
Chr3:178129495..197837190 [GRCh37]
Chr3:179612189..199321587 [NCBI36]
Chr3:3q26.32-29
pathogenic
GRCh38/hg38 3q27.2-29(chr3:185920880-198110319)x3 copy number gain See cases [RCV000051738] Chr3:185920880..198110319 [GRCh38]
Chr3:185638668..197837190 [GRCh37]
Chr3:187121362..199321587 [NCBI36]
Chr3:3q27.2-29
pathogenic
GRCh38/hg38 3q13.11-29(chr3:103426882-198110178)x3 copy number gain See cases [RCV000134948] Chr3:103426882..198110178 [GRCh38]
Chr3:103145726..197837049 [GRCh37]
Chr3:104628416..199321446 [NCBI36]
Chr3:3q13.11-29
pathogenic
GRCh38/hg38 3q26.2-29(chr3:168167568-198110178)x3 copy number gain See cases [RCV000137106] Chr3:168167568..198110178 [GRCh38]
Chr3:167885356..197837049 [GRCh37]
Chr3:169368050..199321446 [NCBI36]
Chr3:3q26.2-29
pathogenic
GRCh38/hg38 3q26.32-29(chr3:176439911-198118383)x3 copy number gain See cases [RCV000138009] Chr3:176439911..198118383 [GRCh38]
Chr3:176157699..197845254 [GRCh37]
Chr3:177640393..199329651 [NCBI36]
Chr3:3q26.32-29
pathogenic|likely benign
GRCh38/hg38 3q27.3-29(chr3:186765148-194409416)x1 copy number loss See cases [RCV000137962] Chr3:186765148..194409416 [GRCh38]
Chr3:186482937..194130145 [GRCh37]
Chr3:187965631..195611434 [NCBI36]
Chr3:3q27.3-29
pathogenic|likely benign
GRCh38/hg38 3q26.32-29(chr3:176168525-198118383)x3 copy number gain See cases [RCV000138662] Chr3:176168525..198118383 [GRCh38]
Chr3:175886313..197845254 [GRCh37]
Chr3:177369007..199329651 [NCBI36]
Chr3:3q26.32-29
pathogenic
GRCh38/hg38 3q25.1-29(chr3:152100512-198118383)x3 copy number gain See cases [RCV000139435] Chr3:152100512..198118383 [GRCh38]
Chr3:151818301..197845254 [GRCh37]
Chr3:153300991..199329651 [NCBI36]
Chr3:3q25.1-29
pathogenic
GRCh38/hg38 3q27.2-27.3(chr3:184843627-187461008)x3 copy number gain See cases [RCV000139009] Chr3:184843627..187461008 [GRCh38]
Chr3:184561415..187178796 [GRCh37]
Chr3:186044109..188661490 [NCBI36]
Chr3:3q27.2-27.3
pathogenic
GRCh38/hg38 3q25.31-29(chr3:156321878-198113452)x3 copy number gain See cases [RCV000140849] Chr3:156321878..198113452 [GRCh38]
Chr3:156039667..197840323 [GRCh37]
Chr3:157522361..199324720 [NCBI36]
Chr3:3q25.31-29
pathogenic
GRCh38/hg38 3q25.31-29(chr3:156118441-198125115)x3 copy number gain See cases [RCV000142310] Chr3:156118441..198125115 [GRCh38]
Chr3:155836230..197851986 [GRCh37]
Chr3:157318924..199336383 [NCBI36]
Chr3:3q25.31-29
pathogenic
GRCh38/hg38 3q26.1-28(chr3:167717962-188365272)x3 copy number gain See cases [RCV000142107] Chr3:167717962..188365272 [GRCh38]
Chr3:167435750..188083060 [GRCh37]
Chr3:168918444..189565754 [NCBI36]
Chr3:3q26.1-28
likely pathogenic
GRCh38/hg38 3q26.33-28(chr3:181138664-192512023)x1 copy number loss See cases [RCV000142019] Chr3:181138664..192512023 [GRCh38]
Chr3:180856452..192229812 [GRCh37]
Chr3:182339146..193712506 [NCBI36]
Chr3:3q26.33-28
pathogenic
GRCh38/hg38 3q26.1-29(chr3:166137209-198125115)x3 copy number gain See cases [RCV000143694] Chr3:166137209..198125115 [GRCh38]
Chr3:165854997..197851986 [GRCh37]
Chr3:167337691..199336383 [NCBI36]
Chr3:3q26.1-29
pathogenic
GRCh37/hg19 3q24-29(chr3:142995020-192997215)x4 copy number gain See cases [RCV000240256] Chr3:142995020..192997215 [GRCh37]
Chr3:3q24-29
pathogenic
GRCh37/hg19 3q27.3-28(chr3:186291045-191037240)x1 copy number loss See cases [RCV000240447] Chr3:186291045..191037240 [GRCh37]
Chr3:3q27.3-28
pathogenic
GRCh37/hg19 3q25.32-29(chr3:158980631-197766890)x3 copy number gain See cases [RCV000447464] Chr3:158980631..197766890 [GRCh37]
Chr3:3q25.32-29
pathogenic
GRCh37/hg19 3q26.33-29(chr3:181911498-197851986)x4 copy number gain See cases [RCV000446732] Chr3:181911498..197851986 [GRCh37]
Chr3:3q26.33-29
pathogenic
GRCh37/hg19 3q25.2-29(chr3:152356847-197851986)x3 copy number gain See cases [RCV000448608] Chr3:152356847..197851986 [GRCh37]
Chr3:3q25.2-29
pathogenic
GRCh37/hg19 3q27.2-27.3(chr3:185419048-186575415)x1 copy number loss See cases [RCV000448264] Chr3:185419048..186575415 [GRCh37]
Chr3:3q27.2-27.3
pathogenic
GRCh37/hg19 3q27.1-27.3(chr3:183178932-186838042)x1 copy number loss See cases [RCV000448937] Chr3:183178932..186838042 [GRCh37]
Chr3:3q27.1-27.3
pathogenic
NC_000003.11:g.(?_186256465)_(186980528_?)del deletion 3MC syndrome 1 [RCV000638455] Chr3:186256465..186980528 [GRCh37]
Chr3:3q27.3
pathogenic|likely pathogenic
GRCh37/hg19 3p26.3-q29(chr3:61892-197851986)x3 copy number gain See cases [RCV000511055] Chr3:61892..197851986 [GRCh37]
Chr3:3p26.3-q29
pathogenic
GRCh37/hg19 3p26.3-q29(chr3:61892-197851986) copy number gain See cases [RCV000512358] Chr3:61892..197851986 [GRCh37]
Chr3:3p26.3-q29
pathogenic
GRCh37/hg19 3q27.1-28(chr3:184300169-188285627) copy number loss Short stature [RCV000626533] Chr3:184300169..188285627 [GRCh37]
Chr3:3q27.1-28
pathogenic
GRCh37/hg19 3q26.33-29(chr3:182539234-197851986)x3 copy number gain not provided [RCV000682336] Chr3:182539234..197851986 [GRCh37]
Chr3:3q26.33-29
pathogenic
GRCh37/hg19 3q26.33-28(chr3:182650681-191275809)x1 copy number loss not provided [RCV000682337] Chr3:182650681..191275809 [GRCh37]
Chr3:3q26.33-28
pathogenic
GRCh37/hg19 3q27.1-29(chr3:184003967-197851986)x3 copy number gain not provided [RCV000682339] Chr3:184003967..197851986 [GRCh37]
Chr3:3q27.1-29
pathogenic
GRCh37/hg19 3q27.3-29(chr3:186374365-197851986)x3 copy number gain not provided [RCV000682341] Chr3:186374365..197851986 [GRCh37]
Chr3:3q27.3-29
pathogenic
GRCh37/hg19 3p26.3-q29(chr3:61495-197838262)x3 copy number gain not provided [RCV000742138] Chr3:61495..197838262 [GRCh37]
Chr3:3p26.3-q29
pathogenic
GRCh37/hg19 3p26.3-q29(chr3:60174-197948027)x3 copy number gain not provided [RCV000742133] Chr3:60174..197948027 [GRCh37]
Chr3:3p26.3-q29
pathogenic
GRCh37/hg19 3q26.31-29(chr3:173281266-197838262)x3 copy number gain not provided [RCV000742968] Chr3:173281266..197838262 [GRCh37]
Chr3:3q26.31-29
pathogenic
GRCh37/hg19 3q27.3-28(chr3:186018854-189514047)x1 copy number loss not provided [RCV000743033] Chr3:186018854..189514047 [GRCh37]
Chr3:3q27.3-28
pathogenic
GRCh37/hg19 3q27.3-29(chr3:186374671-197838262)x3 copy number gain not provided [RCV000743037] Chr3:186374671..197838262 [GRCh37]
Chr3:3q27.3-29
pathogenic
GRCh37/hg19 3q27.3(chr3:186504407-186510454)x3 copy number gain not provided [RCV000743041] Chr3:186504407..186510454 [GRCh37]
Chr3:3q27.3
benign
GRCh37/hg19 3q27.2-27.3(chr3:185879162-187446035)x1 copy number loss not provided [RCV001005497] Chr3:185879162..187446035 [GRCh37]
Chr3:3q27.2-27.3
pathogenic
GRCh37/hg19 3q27.3(chr3:186493742-186672011)x3 copy number gain not provided [RCV000848730] Chr3:186493742..186672011 [GRCh37]
Chr3:3q27.3
uncertain significance
GRCh37/hg19 3q27.3(chr3:186493742-186672007)x3 copy number gain not provided [RCV000847416] Chr3:186493742..186672007 [GRCh37]
Chr3:3q27.3
uncertain significance
GRCh37/hg19 3q26.2-28(chr3:169617690-190593854)x3 copy number gain not provided [RCV001005487] Chr3:169617690..190593854 [GRCh37]
Chr3:3q26.2-28
pathogenic
NC_000003.11:g.(?_186256465)_(187009440_?)del deletion 3MC syndrome 1 [RCV001033360] Chr3:186256465..187009440 [GRCh37]
Chr3:3q27.3
pathogenic
GRCh37/hg19 3q27.3(chr3:186493742-186668140)x3 copy number gain not provided [RCV001259732] Chr3:186493742..186668140 [GRCh37]
Chr3:3q27.3
likely benign
GRCh37/hg19 3q27.1-27.3(chr3:182877291-186830759)x1 copy number loss not provided [RCV001259730] Chr3:182877291..186830759 [GRCh37]
Chr3:3q27.1-27.3
pathogenic
GRCh37/hg19 3q26.31-27.3(chr3:175119199-187592480)x3 copy number gain not provided [RCV001795540] Chr3:175119199..187592480 [GRCh37]
Chr3:3q26.31-27.3
pathogenic
GRCh37/hg19 3q26.33-27.3(chr3:182189525-187212935) copy number loss not specified [RCV002053393] Chr3:182189525..187212935 [GRCh37]
Chr3:3q26.33-27.3
pathogenic
GRCh37/hg19 3q27.1-27.3(chr3:183178932-186838042) copy number loss not specified [RCV002053395] Chr3:183178932..186838042 [GRCh37]
Chr3:3q27.1-27.3
pathogenic
GRCh37/hg19 3q27.3(chr3:186149060-186599706) copy number loss not specified [RCV002053397] Chr3:186149060..186599706 [GRCh37]
Chr3:3q27.3
uncertain significance
NC_000003.11:g.(?_186256485)_(187009420_?)dup duplication 3MC syndrome 1 [RCV003119728]|not provided [RCV003119729] Chr3:186256485..187009420 [GRCh37]
Chr3:3q27.3
uncertain significance|no classifications from unflagged records
GRCh37/hg19 3q27.1-28(chr3:183556940-188083060) copy number loss Short stature [RCV002280742] Chr3:183556940..188083060 [GRCh37]
Chr3:3q27.1-28
pathogenic
GRCh37/hg19 3q26.31-29(chr3:171558472-197871052)x3 copy number gain Isolated anorectal malformation [RCV002286610] Chr3:171558472..197871052 [GRCh37]
Chr3:3q26.31-29
likely pathogenic
GRCh37/hg19 3q27.1-29(chr3:183498520-197851986)x3 copy number gain See cases [RCV002286344] Chr3:183498520..197851986 [GRCh37]
Chr3:3q27.1-29
pathogenic
GRCh37/hg19 3q27.1-28(chr3:184170962-188047867)x1 copy number loss not provided [RCV002474891] Chr3:184170962..188047867 [GRCh37]
Chr3:3q27.1-28
likely pathogenic
Single allele duplication not provided [RCV003448680] Chr3:140154329..197847235 [GRCh37]
Chr3:3q23-29
pathogenic
Single allele duplication not provided [RCV003448704] Chr3:176412210..197847235 [GRCh37]
Chr3:3q26.32-29
pathogenic
GRCh37/hg19 3q26.33-29(chr3:179313373-197851444)x3 copy number gain See cases [RCV004442807] Chr3:179313373..197851444 [GRCh37]
Chr3:3q26.33-29
pathogenic
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:72
Count of miRNA genes:71
Interacting mature miRNAs:71
Transcripts:ENST00000408493
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
167 303 267 225 451 217 284 1 46 93 27 299 539 598 1 287 60 210 230 20

Sequence


Ensembl Acc Id: ENST00000408493
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl3186,786,675 - 186,786,852 (+)Ensembl
RefSeq Acc Id: NR_002989
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh383186,786,676 - 186,786,852 (+)NCBI
GRCh373186,504,464 - 186,504,641 (+)RGD
Build 363187,987,158 - 187,987,335 (+)NCBI Archive
Celera3184,940,626 - 184,940,803 (+)RGD
HuRef3183,914,141 - 183,914,318 (+)ENTREZGENE
CHM1_13186,468,041 - 186,468,218 (+)NCBI
T2T-CHM13v2.03189,608,706 - 189,608,882 (+)NCBI
Sequence:
Promoters
RGD ID:6800974
Promoter ID:HG_KWN:47105
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:ENST00000362560,   ENST00000363548,   ENST00000408493,   OTTHUMT00000344615,   OTTHUMT00000344629,   OTTHUMT00000344630,   OTTHUMT00000344631,   OTTHUMT00000344632,   OTTHUMT00000344633,   OTTHUMT00000344634,   OTTHUMT00000344635
Position:
Human AssemblyChrPosition (strand)Source
Build 363187,985,591 - 187,988,297 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
COSMIC SNORA81 COSMIC
Ensembl Genes ENSG00000221420 Ensembl, ENTREZGENE
Ensembl Transcript ENST00000408493 ENTREZGENE
GTEx ENSG00000221420 GTEx
HGNC ID HGNC:32667 ENTREZGENE
Human Proteome Map SNORA81 Human Proteome Map
NCBI Gene 677847 ENTREZGENE
OMIM 611334 OMIM
PharmGKB PA144596283 PharmGKB
RNAcentral URS00025E358E RNACentral