Glod5 (glyoxalase domain containing 5) - Rat Genome Database

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Gene: Glod5 (glyoxalase domain containing 5) Mus musculus
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Symbol: Glod5
Name: glyoxalase domain containing 5
RGD ID: 1557832
MGI Page MGI
Description: Is expressed in lung and pituitary gland. Orthologous to human GLOD5 (glyoxalase domain containing 5).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 2010001H14Rik; AV061890; glyoxalase domain-containing protein 5; RP23-198C2.7
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X7,870,440 - 7,884,731 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX7,870,439 - 7,884,731 (-)EnsemblGRCm39 Ensembl
GRCm38X8,004,201 - 8,018,492 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX8,004,200 - 8,018,492 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X7,581,327 - 7,595,618 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X7,161,160 - 7,175,451 (-)NCBIMGSCv36mm8
CeleraX3,450,712 - 3,464,719 (+)NCBICelera
Cytogenetic MapXA1.1NCBI
cM MapX3.61NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
4. Mouse MP Annotation Import Pipeline RGD automated import pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:12477932   PMID:14610273   PMID:16141072   PMID:16141073   PMID:17062627   PMID:18799693   PMID:20548051   PMID:21267068  


Genomics

Comparative Map Data
Glod5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X7,870,440 - 7,884,731 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX7,870,439 - 7,884,731 (-)EnsemblGRCm39 Ensembl
GRCm38X8,004,201 - 8,018,492 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX8,004,200 - 8,018,492 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X7,581,327 - 7,595,618 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X7,161,160 - 7,175,451 (-)NCBIMGSCv36mm8
CeleraX3,450,712 - 3,464,719 (+)NCBICelera
Cytogenetic MapXA1.1NCBI
cM MapX3.61NCBI
GLOD5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X48,761,747 - 48,773,648 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX48,761,747 - 48,773,648 (+)EnsemblGRCh38hg38GRCh38
GRCh37X48,620,151 - 48,632,064 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X48,508,985 - 48,516,795 (+)NCBINCBI36Build 36hg18NCBI36
CeleraX53,031,515 - 53,043,857 (-)NCBICelera
Cytogenetic MapXp11.23NCBI
HuRefX46,281,675 - 46,289,876 (+)NCBIHuRef
CHM1_1X48,651,323 - 48,663,204 (+)NCBICHM1_1
T2T-CHM13v2.0X48,172,222 - 48,184,150 (+)NCBIT2T-CHM13v2.0
Glod5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X17,145,936 - 17,160,733 (+)NCBIGRCr8
mRatBN7.2X14,473,994 - 14,488,797 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX14,473,994 - 14,488,683 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX19,287,411 - 19,302,084 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X20,781,023 - 20,795,686 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X17,046,193 - 17,060,859 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X15,225,645 - 15,240,458 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX15,225,645 - 15,240,329 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X16,006,589 - 16,021,387 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X26,505,715 - 26,520,399 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX14,558,775 - 14,573,352 (+)NCBICelera
Cytogenetic MapXq12NCBI
Glod5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955543319,985 - 323,393 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955543320,087 - 321,311 (+)NCBIChiLan1.0ChiLan1.0
GLOD5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X50,250,748 - 50,263,035 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X50,254,120 - 50,266,407 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X41,060,152 - 41,071,654 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X48,920,747 - 48,932,442 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX48,920,747 - 48,932,442 (+)Ensemblpanpan1.1panPan2
GLOD5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X41,967,674 - 41,979,241 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX41,967,812 - 41,979,243 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX16,343,245 - 16,354,675 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X42,103,951 - 42,115,447 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX42,104,009 - 42,115,457 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X42,090,023 - 42,101,685 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X42,078,509 - 42,089,940 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X42,172,427 - 42,184,091 (+)NCBIUU_Cfam_GSD_1.0
Glod5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X34,479,155 - 34,491,347 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936721719,651 - 732,078 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936721719,660 - 731,800 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GLOD5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX42,877,140 - 42,889,271 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X42,877,034 - 42,889,285 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
GLOD5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X45,888,220 - 45,900,316 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX45,888,509 - 45,900,095 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607611,368,482 - 11,380,354 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Glod5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624893562,330 - 574,594 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624893562,815 - 570,099 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Glod5
196 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:91
Count of miRNA genes:84
Interacting mature miRNAs:86
Transcripts:ENSMUST00000033503
Prediction methods:Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1302195Pbwg10_mpostnatal body weight growth 10 (mouse)Not determinedX126202173Mouse
1357433Dbts2_mdiabetes 2 (mouse)Not determinedX7226295150107038Mouse

Markers in Region
AV061890  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38X8,004,272 - 8,004,411UniSTSGRCm38
MGSCv37X7,581,398 - 7,581,537UniSTSGRCm37
CeleraX3,464,509 - 3,464,648UniSTS
Cytogenetic MapXA1.1UniSTS
Whitehead/MRC_RHX75.34UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000033503   ⟹   ENSMUSP00000033503
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX7,870,439 - 7,884,731 (-)Ensembl
GRCm38.p6 EnsemblX8,004,200 - 8,018,492 (-)Ensembl
RefSeq Acc Id: NM_027227   ⟹   NP_081503
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X7,870,440 - 7,884,731 (-)NCBI
GRCm38X8,004,201 - 8,018,492 (-)NCBI
MGSCv37X7,581,327 - 7,595,618 (-)RGD
CeleraX3,450,712 - 3,464,719 (+)RGD
cM MapX ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006527699   ⟹   XP_006527762
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X7,870,442 - 7,882,043 (-)NCBI
GRCm38X8,004,203 - 8,015,804 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_081503 (Get FASTA)   NCBI Sequence Viewer  
  XP_006527762 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH61027 (Get FASTA)   NCBI Sequence Viewer  
  BAB25406 (Get FASTA)   NCBI Sequence Viewer  
  EDL33939 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000033503
  ENSMUSP00000033503.3
GenBank Protein Q9D8I3 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_081503   ⟸   NM_027227
- UniProtKB: Q9D8I3 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006527762   ⟸   XM_006527699
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSMUSP00000033503   ⟸   ENSMUST00000033503
Protein Domains
VOC

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9D8I3-F1-model_v2 AlphaFold Q9D8I3 1-148 view protein structure

Promoters
RGD ID:6845743
Promoter ID:MM_KWN:59467
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney
Transcripts:OTTMUST00000043494
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36X7,595,166 - 7,595,666 (-)MPROMDB
RGD ID:13680024
Promoter ID:EPDNEW_M24161
Type:initiation region
Name:Glod5_1
Description:Mus musculus glyoxalase domain containing 5 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38X8,018,458 - 8,018,518EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1917074 AgrOrtholog
Ensembl Genes ENSMUSG00000031163 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000033503 ENTREZGENE
  ENSMUST00000033503.3 UniProtKB/Swiss-Prot
Gene3D-CATH 3.10.180.10 UniProtKB/Swiss-Prot
InterPro Glyas_Bleomycin-R_OHBP_Dase UniProtKB/Swiss-Prot
  Glyas_Fos-R_dOase_dom UniProtKB/Swiss-Prot
  GlyoxalaseI/FosfomycinResist UniProtKB/Swiss-Prot
  VOC UniProtKB/Swiss-Prot
KEGG Report mmu:69824 UniProtKB/Swiss-Prot
MGD MGI:1917074 ENTREZGENE
NCBI Gene 69824 ENTREZGENE
PANTHER GLYOXALASE DOMAIN-CONTAINING PROTEIN 5 UniProtKB/Swiss-Prot
  GLYOXALASE FAMILY PROTEIN UniProtKB/Swiss-Prot
Pfam Glyoxalase UniProtKB/Swiss-Prot
PhenoGen Glod5 PhenoGen
PROSITE VOC UniProtKB/Swiss-Prot
Superfamily-SCOP SSF54593 UniProtKB/Swiss-Prot
UniProt GLOD5_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE