LOC127396574 (NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:9834089-9834615) - Rat Genome Database

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Gene: LOC127396574 (NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:9834089-9834615) Homo sapiens
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Symbol: LOC127396574
Name: NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:9834089-9834615
RGD ID: 155654028
Description: This genomic region includes an enhancer that was validated by the ChIP-STARR-seq massively parallel reporter assay (MPRA) in primed human embryonic stem cells, where it associates with the NANOG transcription factor and is marked by the H3K27ac and H3K4me1 histone modifications. This locus also includes two accessible chromatin subregions, one of which was validated as an enhancer and the other as a silencer based on their ability to activate or repress an origin of replication minimal core promoter by the ATAC-STARR-seq (assay for transposase-accessible chromatin with self-transcribing active regulatory region sequencing) MPRA in GM12878 lymphoblastoid cells. [provided by RefSeq, Jun 2023]
Type: biological-region
RefSeq Status: REVIEWED
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3839,792,405 - 9,792,957 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3739,834,089 - 9,834,641 (+)NCBIGRCh37GRCh37hg19GRCh37
T2T-CHM13v2.039,784,359 - 9,784,911 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:30033119   PMID:35858748  


Genomics


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2316345GLUCO224_HGlucose level QTL 224 (human)1.270.008Glucose level3121543441Human


Expression

RNA-SEQ Expression


Sequence



Additional Information

Database Acc Id Source(s)
COSMIC LOC127396574 COSMIC
GTEx LOC127396574 GTEx
Human Proteome Map LOC127396574 Human Proteome Map
NCBI Gene LOC127396574 ENTREZGENE