Or11h7 (olfactory receptor family 11 subfamily H member 7)

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Gene: Or11h7 (olfactory receptor family 11 subfamily H member 7) Mus musculus

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Symbol:

Or11h7

Name:

olfactory receptor family 11 subfamily H member 7

RGD ID:

1551738

MGI Page

MGI

Description:

Predicted to enable olfactory receptor activity. Predicted to act upstream of or within G protein-coupled receptor signaling pathway and sensory perception of smell. Predicted to be located in membrane. Orthologous to human OR11H7 (olfactory receptor family 11 subfamily H member 7 (gene/pseudogene)).

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

GA_x6K02T2PMLR-6372116-6373060; MOR106-; MOR106-12; olfactory receptor 746; olfactory receptor MOR106-12; Olfr746

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCm39 - Mouse Genome Assembly GRCm39

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	14	50,890,696 - 50,891,640 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	14	50,884,540 - 50,891,640 (+)	Ensembl		GRCm39 Ensembl
GRCm38	14	50,653,239 - 50,654,183 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	14	50,647,083 - 50,654,183 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	14	51,272,914 - 51,273,858 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	14	49,575,190 - 49,576,134 (+)	NCBI		MGSCv36	mm8
Celera	14	46,912,948 - 46,913,892 (+)	NCBI		Celera
Cytogenetic Map	14	C1	NCBI
cM Map	14	26.19	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

4,4'-diaminodiphenylmethane (EXP)

bisphenol A (ISO)

C60 fullerene (ISO)

sodium arsenite (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

G protein-coupled receptor signaling pathway (ISA)

sensory perception of smell (ISA)

Cellular Component

membrane (ISA)

Molecular Function

olfactory receptor activity (ISA)

References

References - curated

#	Reference Title	Reference Citation
1.	MGDs mouse GO annotations	MGD data from the GO Consortium
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:11802173	PMID:11875048	PMID:14611657	PMID:21873635	PMID:32295537

Genomics

Comparative Map Data

Or11h7
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	14	50,890,696 - 50,891,640 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	14	50,884,540 - 50,891,640 (+)	Ensembl		GRCm39 Ensembl
GRCm38	14	50,653,239 - 50,654,183 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	14	50,647,083 - 50,654,183 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	14	51,272,914 - 51,273,858 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	14	49,575,190 - 49,576,134 (+)	NCBI		MGSCv36	mm8
Celera	14	46,912,948 - 46,913,892 (+)	NCBI		Celera
Cytogenetic Map	14	C1	NCBI
cM Map	14	26.19	NCBI

OR11H7
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	14	20,228,981 - 20,230,749 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	14	20,229,402 - 20,230,346 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	14	20,697,140 - 20,698,908 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	14	19,767,301 - 19,768,442 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	14	559,075 - 560,016 (+)	NCBI		Celera
Cytogenetic Map	14	q11.2	NCBI
HuRef	14	819,548 - 820,489 (+)	NCBI		HuRef
CHM1_1	14	20,698,520 - 20,699,461 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	14	14,423,610 - 14,425,378 (+)	NCBI		T2T-CHM13v2.0

Or11h23b
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	15	26,280,168 - 26,281,106 (+)	NCBI		GRCr8
mRatBN7.2	15	23,806,594 - 23,807,532 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	15	23,806,594 - 23,807,532 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	15	26,577,823 - 26,578,761 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	15	27,539,168 - 27,540,106 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	15	25,786,375 - 25,787,313 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	15	27,438,853 - 27,439,791 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	15	27,438,853 - 27,439,791 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	15	31,374,818 - 31,375,756 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	15	26,340,325 - 26,341,263 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	15	26,356,024 - 26,356,963 (+)	NCBI
Celera	15	24,135,353 - 24,136,291 (+)	NCBI		Celera
Cytogenetic Map	15	p14	NCBI

OR11H7
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	15	17,597,625 - 17,598,758 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	15	17,597,814 - 17,598,758 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	15	18,082,755 - 18,083,705 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	15	17,856,043 - 17,856,993 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	15	17,856,049 - 17,856,993 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	15	17,539,526 - 17,540,474 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	15	17,593,156 - 17,594,106 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	15	17,722,819 - 17,723,769 (+)	NCBI		UU_Cfam_GSD_1.0

LOC100152678
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	78,653,508 - 78,654,545 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	7	78,653,425 - 78,654,458 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	83,681,917 - 83,682,867 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

Variants

Variants in Or11h7
27 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	68
Count of miRNA genes:	61
Interacting mature miRNAs:	66
Transcripts:	ENSMUST00000080616
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCm39)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1357589	Kdnw2_m	kidney weight 2 (mouse)			Not determined		14	20887473	121269804	Mouse
1300625	Cosz2_m	cocaine seizure 2 (mouse)			Not determined		14	35045797	68785736	Mouse
1301777	Bglq15_m	body growth late QTL 15 (mouse)			Not determined		14	42962416	76962593	Mouse
1357527	Epfpq1_m	epididymal fat percentage QTL 1 (mouse)			Not determined		14	21062450	71885801	Mouse
1301424	Skull21_m	skull morphology 21 (mouse)			Not determined		14	42962416	76962593	Mouse
27226744	Metcl6_m	metatarsal-calcaneal length 6, 5 week (mouse)					14	30321957	52937457	Mouse
4141400	Nilac8_m	nicotine induced locomotor activity 8 (mouse)			Not determined		14	43065847	77066045	Mouse
27226774	Tibl15_m	tibia length 15, 10 week (mouse)					14	30321957	87937436	Mouse
4142485	Modor2_m	modifier of ocular retardation 2 (mouse)			Not determined		14	24926248	58179769	Mouse
4142419	Tgq26_m	triglyceride QTL 26 (mouse)			Not determined			40337319	74337319	Mouse
27226737	Metcl12_m	metatarsal-calcaneal length 12, 10 week (mouse)					14	33221957	59437449	Mouse
1300605	El5_m	epilepsy 5 (mouse)			Not determined		14	49455425	83455556	Mouse
1301372	Sluc13_m	susceptibility to lung cancer 13 (mouse)			Not determined		14	18827604	52827726	Mouse
1301091	Bbaa21_m	B.burgdorferi-associated arthritis 21 (mouse)			Not determined		14	43065847	77066045	Mouse
4141484	Hcbip1_m	hexachlorobenzene induced porphyria 1 (mouse)			Not determined			47335250	59962593	Mouse
1300998	Cia17_m	collagen induced arthritis 17 (mouse)			Not determined		14	30335250	64335381	Mouse
10043887	Cia50_m	collagen induced arthritis QTL 50 (mouse)			Not determined		14	37430185	71430320	Mouse
1300805	Mors3_m	modifier of obesity related sterility 3 (mouse)			Not determined		14	43037270	77037418	Mouse
10043886	Cia49_m	collagen induced arthritis QTL 49 (mouse)			Not determined		14	29996994	63997133	Mouse
27226727	Tibl21_m	tibia length 21, 16 week (mouse)					14	34121957	52937457	Mouse
14746973	Manh76_m	mandible shape 76 (mouse)					14	22287217	56287217	Mouse
1300909	Ath13_m	atherosclerosis 13 (mouse)			Not determined		14	30335250	64335381	Mouse
13506929	Recrq10_m	recombination rate in male meiosis QTL 10 (mouse)					14	27921957	61137449	Mouse

Markers in Region

UniSTS:492653

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	14	50,653,139 - 50,654,241	UniSTS	GRCm38
MGSCv37	14	51,272,814 - 51,273,916	UniSTS	GRCm37
Celera	14	46,912,848 - 46,913,950	UniSTS
Cytogenetic Map	14	C3-D1	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_146298	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC140280	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY073795	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY317871	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSMUST00000080616 ⟹ ENSMUSP00000079451

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	14	50,890,696 - 50,891,640 (+)	Ensembl
GRCm38.p6 Ensembl	14	50,653,239 - 50,654,183 (+)	Ensembl

Ensembl Acc Id:

ENSMUST00000218546 ⟹ ENSMUSP00000151399

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	14	50,884,540 - 50,891,640 (+)	Ensembl
GRCm38.p6 Ensembl	14	50,647,083 - 50,654,183 (+)	Ensembl

RefSeq Acc Id:

NM_146298 ⟹ NP_666410

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	14	50,890,696 - 50,891,640 (+)	NCBI
GRCm38	14	50,653,239 - 50,654,183 (+)	ENTREZGENE
MGSCv37	14	51,272,914 - 51,273,858 (+)	RGD
Celera	14	46,912,948 - 46,913,892 (+)	RGD
cM Map	14		ENTREZGENE

Sequence:

show sequence

ATGAACGTGTCAGAGGGATCCACGGTGACATATTTTGTCTTATTGGGATTCCCTGGTCCCTGGA
AGATTCAAATCATACTTTTCTCACTGATTCTGCTGCTCTACATGATAACTTTGACTGGGAATAT
GGCCATCATTTGTGCAGTGAGATGGAACCAACAACTCCACACCCCTATGTATATGTTCCTGGCC
AACTTCTCCTTCCTAGAAATCTGGTACGTGACCTGCACAGTTCCCAACATGCTGGTCAACTCTC
TTTCCAAAACTAAGACTATATCCTTCACTGGATGCTTTACTCAGTTCTACTTCTTCTTCTCCCT
GGGCACAACTGAATGCTTCTTCCTCTGTGCCATGGCTTATGATCGGTACCTAGCCATCTGCTAC
CCACTGCACTATCCTTCCATCATGACTAGGCAATTCTGCAGTATTCTGATGTCCCTCTGTTGGA
TCATTGGTTTCTCTGCACATTTGATTCCCATTTTCTTTATTTCTCAATTGTCTTTCTGTGGCCC
CAATATCATTGATCACTTTCTCTGTGATGTGGACCCACTAATAGCACTGTCCTGTACCCCTACA
CACATCATAAGGCATGTATTCTATTCTATAAGTACTCTTATCATTATTCTCACTGGTTTGTACA
TCCTTGGATCTTATGCCTTGGAGCTCAGAGCTGTTCTTCAGGTTCCTTCTTCAGATGGACGTCA
AAAGGCCTTCTCAACCTGTGGATCCCACCTGCTGGTAGTGTCTCTGTTCTATGGAACCATAATG
GTGATGTATGTCAGCCCCACATCTGGCAACTCAGTTGACATGAATAAAATTATCACACTGATAT
ATTCTGTGGTGACACCAGCTTTAAATCCTTTCATCTATAGTCTGCGTAACAAGGATATGAAATA
TGCTCTCCATCATGTCTTCTTTGGGAATAGCATTATGCAAAACTTATAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_666410	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAL61458	(Get FASTA)	NCBI Sequence Viewer
	AAP71207	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSMUSP00000079451
	ENSMUSP00000079451.3
	ENSMUSP00000151399.2

RefSeq Acc Id:

NP_666410 ⟸ NM_146298

- UniProtKB:

E9Q840 (UniProtKB/TrEMBL), Q8VEV3 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MNVSEGSTVTYFVLLGFPGPWKIQIILFSLILLLYMITLTGNMAIICAVRWNQQLHTPMYMFLA
NFSFLEIWYVTCTVPNMLVNSLSKTKTISFTGCFTQFYFFFSLGTTECFFLCAMAYDRYLAICY
PLHYPSIMTRQFCSILMSLCWIIGFSAHLIPIFFISQLSFCGPNIIDHFLCDVDPLIALSCTPT
HIIRHVFYSISTLIIILTGLYILGSYALELRAVLQVPSSDGRQKAFSTCGSHLLVVSLFYGTIM
VMYVSPTSGNSVDMNKIITLIYSVVTPALNPFIYSLRNKDMKYALHHVFFGNSIMQNL

hide sequence

Ensembl Acc Id:

ENSMUSP00000151399 ⟸ ENSMUST00000218546

Ensembl Acc Id:

ENSMUSP00000079451 ⟸ ENSMUST00000080616

Protein Domains

G-protein coupled receptors family 1 profile

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-E9Q840-F1-model_v2	AlphaFold	E9Q840	1-314	view protein structure

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	MGI:3030580	AgrOrtholog
Ensembl Genes	ENSMUSG00000058188	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSMUST00000080616	ENTREZGENE
	ENSMUST00000080616.3	UniProtKB/TrEMBL
	ENSMUST00000218546.2	UniProtKB/TrEMBL
Gene3D-CATH	Rhodopsin 7-helix transmembrane proteins	UniProtKB/TrEMBL
InterPro	7TM_GPCR_Rhodpsn	UniProtKB/TrEMBL
	GPCR_Rhodpsn_supfam	UniProtKB/TrEMBL
	Olfact_rcpt	UniProtKB/TrEMBL
	Olfactory_GPCR1	UniProtKB/TrEMBL
KEGG Report	mmu:258295	UniProtKB/TrEMBL
MGD	MGI:3030580	ENTREZGENE
NCBI Gene	258295	ENTREZGENE
PANTHER	G-PROTEIN COUPLED RECEPTOR	UniProtKB/TrEMBL
	OLFACTORY RECEPTOR 11H7	UniProtKB/TrEMBL
Pfam	7tm_4	UniProtKB/TrEMBL
PhenoGen	Or11h7	PhenoGen
PRINTS	GPCRRHODOPSN	UniProtKB/TrEMBL
	OLFACTORYR	UniProtKB/TrEMBL
PROSITE	G_PROTEIN_RECEP_F1_1	UniProtKB/TrEMBL
	G_PROTEIN_RECEP_F1_2	UniProtKB/TrEMBL
Superfamily-SCOP	Family A G protein-coupled receptor-like	UniProtKB/TrEMBL
UniProt	E9Q840	ENTREZGENE, UniProtKB/TrEMBL
	Q8VEV3	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2022-05-23	Or11h7	olfactory receptor family 11 subfamily H member 7	Olfr746	olfactory receptor 746	Symbol and/or name updated	27372883	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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