TRDV1 (T cell receptor delta variable 1) - Rat Genome Database

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Gene: TRDV1 (T cell receptor delta variable 1) Homo sapiens
Analyze
Symbol: TRDV1
Name: T cell receptor delta variable 1
RGD ID: 1352101
HGNC Page HGNC:12262
Description: Predicted to be involved in immune response. Predicted to be located in plasma membrane. Predicted to be part of immunoglobulin complex.
Type: gene (Ensembl: TR_V_gene)
RefSeq Status: REVIEWED
Previously known as: hDV101S1
RGD Orthologs
Mouse
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381422,096,050 - 22,096,619 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1422,096,032 - 22,096,619 (+)EnsemblGRCh38hg38GRCh38
GRCh371422,564,327 - 22,564,896 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361421,634,167 - 21,634,736 (+)NCBINCBI36Build 36hg18NCBI36
Celera142,427,886 - 2,428,455 (+)NCBICelera
Cytogenetic Map14q11.2NCBI
HuRef142,682,190 - 2,682,759 (+)NCBIHuRef
CHM1_11422,563,952 - 22,564,521 (+)NCBICHM1_1
T2T-CHM13v2.01416,293,724 - 16,294,293 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
citric acid  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References
Additional References at PubMed
PMID:3186718   PMID:8951372   PMID:9190911   PMID:21873635  


Genomics

Comparative Map Data
TRDV1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381422,096,050 - 22,096,619 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1422,096,032 - 22,096,619 (+)EnsemblGRCh38hg38GRCh38
GRCh371422,564,327 - 22,564,896 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361421,634,167 - 21,634,736 (+)NCBINCBI36Build 36hg18NCBI36
Celera142,427,886 - 2,428,455 (+)NCBICelera
Cytogenetic Map14q11.2NCBI
HuRef142,682,190 - 2,682,759 (+)NCBIHuRef
CHM1_11422,563,952 - 22,564,521 (+)NCBICHM1_1
T2T-CHM13v2.01416,293,724 - 16,294,293 (+)NCBIT2T-CHM13v2.0
Trav15-1-dv6-1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391453,797,133 - 53,797,704 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1453,797,089 - 53,797,704 (+)EnsemblGRCm39 Ensembl
GRCm381453,559,676 - 53,560,247 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1453,559,632 - 53,560,247 (+)EnsemblGRCm38mm10GRCm38
MGSCv371454,179,351 - 54,179,922 (+)NCBIGRCm37MGSCv37mm9NCBIm37
Celera1449,821,422 - 49,822,074 (+)NCBICelera
Cytogenetic Map14C2NCBI
cM Map1427.42NCBI


Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 14q11.2(chr14:21919243-22511027)x1 copy number loss See cases [RCV000135132] Chr14:21919243..22511027 [GRCh38]
Chr14:22387418..22980010 [GRCh37]
Chr14:21457258..22049850 [NCBI36]
Chr14:14q11.2		 benign
GRCh38/hg38 14q11.2-32.33(chr14:20151149-106855263)x3 copy number gain See cases [RCV000135543] Chr14:20151149..106855263 [GRCh38]
Chr14:20619308..107263478 [GRCh37]
Chr14:19689148..106334523 [NCBI36]
Chr14:14q11.2-32.33		 pathogenic
GRCh38/hg38 14q11.2(chr14:21973760-22442515)x1 copy number loss See cases [RCV000135471] Chr14:21973760..22442515 [GRCh38]
Chr14:22441989..22911507 [GRCh37]
Chr14:21511829..21981347 [NCBI36]
Chr14:14q11.2		 benign
GRCh38/hg38 14q11.2(chr14:21854413-22495939)x1 copy number loss See cases [RCV000135900] Chr14:21854413..22495939 [GRCh38]
Chr14:22322590..22964922 [GRCh37]
Chr14:21392430..22034762 [NCBI36]
Chr14:14q11.2		 benign
GRCh38/hg38 14q11.2-12(chr14:20412587-25018120)x3 copy number gain See cases [RCV000137725] Chr14:20412587..25018120 [GRCh38]
Chr14:20880746..25487326 [GRCh37]
Chr14:19950586..24557166 [NCBI36]
Chr14:14q11.2-12		 likely pathogenic
GRCh38/hg38 14q11.2(chr14:22021665-22324997)x3 copy number gain See cases [RCV000138466] Chr14:22021665..22324997 [GRCh38]
Chr14:22489905..22793429 [GRCh37]
Chr14:21559745..21863269 [NCBI36]
Chr14:14q11.2		 benign|likely benign|conflicting data from submitters
GRCh38/hg38 14q11.2(chr14:21919182-22201679)x3 copy number gain See cases [RCV000139288] Chr14:21919182..22201679 [GRCh38]
Chr14:22387357..22669573 [GRCh37]
Chr14:21457197..21739413 [NCBI36]
Chr14:14q11.2		 likely benign
GRCh38/hg38 14q11.2(chr14:22021665-22428036)x3 copy number gain See cases [RCV000139203] Chr14:22021665..22428036 [GRCh38]
Chr14:22489905..22897028 [GRCh37]
Chr14:21559745..21966868 [NCBI36]
Chr14:14q11.2		 likely benign
GRCh38/hg38 14q11.2(chr14:21973759-22428036)x3 copy number gain See cases [RCV000139486] Chr14:21973759..22428036 [GRCh38]
Chr14:22441988..22897028 [GRCh37]
Chr14:21511828..21966868 [NCBI36]
Chr14:14q11.2		 benign
GRCh38/hg38 14q11.2(chr14:21919182-22398359)x3 copy number gain See cases [RCV000139614] Chr14:21919182..22398359 [GRCh38]
Chr14:22387357..22866762 [GRCh37]
Chr14:21457197..21936602 [NCBI36]
Chr14:14q11.2		 likely benign
GRCh38/hg38 14q11.2(chr14:21010790-22951814)x3 copy number gain See cases [RCV000140829] Chr14:21010790..22951814 [GRCh38]
Chr14:21478949..23421023 [GRCh37]
Chr14:20548789..22490863 [NCBI36]
Chr14:14q11.2		 uncertain significance
GRCh38/hg38 14q11.2(chr14:21830995-22324997)x3 copy number gain See cases [RCV000142945] Chr14:21830995..22324997 [GRCh38]
Chr14:22299151..22793429 [GRCh37]
Chr14:21368991..21863269 [NCBI36]
Chr14:14q11.2		 pathogenic|likely benign
GRCh38/hg38 14q11.2(chr14:22021665-22398359)x3 copy number gain See cases [RCV000142894] Chr14:22021665..22398359 [GRCh38]
Chr14:22489905..22866762 [GRCh37]
Chr14:21559745..21936602 [NCBI36]
Chr14:14q11.2		 likely benign
GRCh38/hg38 14q11.2(chr14:21973759-22398359)x3 copy number gain See cases [RCV000142826] Chr14:21973759..22398359 [GRCh38]
Chr14:22441988..22866762 [GRCh37]
Chr14:21511828..21936602 [NCBI36]
Chr14:14q11.2		 likely benign
GRCh38/hg38 14q11.2(chr14:21973759-22324997)x3 copy number gain See cases [RCV000142998] Chr14:21973759..22324997 [GRCh38]
Chr14:22441988..22793429 [GRCh37]
Chr14:21511828..21863269 [NCBI36]
Chr14:14q11.2		 pathogenic|likely benign
GRCh38/hg38 14q11.2-32.33(chr14:20043514-106877229)x3 copy number gain See cases [RCV000143373] Chr14:20043514..106877229 [GRCh38]
Chr14:20511673..107285437 [GRCh37]
Chr14:19581513..106356482 [NCBI36]
Chr14:14q11.2-32.33		 pathogenic
GRCh38/hg38 14q11.2-21.2(chr14:20022693-44093672)x3 copy number gain See cases [RCV000143186] Chr14:20022693..44093672 [GRCh38]
Chr14:20490852..44562875 [GRCh37]
Chr14:19560692..43632625 [NCBI36]
Chr14:14q11.2-21.2		 pathogenic
GRCh38/hg38 14q11.2-21.3(chr14:20043513-48642042)x3 copy number gain See cases [RCV000143748] Chr14:20043513..48642042 [GRCh38]
Chr14:20511672..49111245 [GRCh37]
Chr14:19581512..48180995 [NCBI36]
Chr14:14q11.2-21.3		 pathogenic
GRCh38/hg38 14q11.2(chr14:19755249-22741281)x1 copy number loss See cases [RCV000051483] Chr14:19755249..22741281 [GRCh38]
Chr14:20223408..23210490 [GRCh37]
Chr14:19293248..22280330 [NCBI36]
Chr14:14q11.2		 pathogenic
GRCh38/hg38 14q11.2-12(chr14:20151149-27723796)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051484]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051484]|See cases [RCV000051484] Chr14:20151149..27723796 [GRCh38]
Chr14:20619308..28193002 [GRCh37]
Chr14:19689148..27262842 [NCBI36]
Chr14:14q11.2-12		 pathogenic
GRCh38/hg38 14q11.2-21.2(chr14:20196945-45284802)x1 copy number loss See cases [RCV000051485] Chr14:20196945..45284802 [GRCh38]
Chr14:20665104..45754005 [GRCh37]
Chr14:19734944..44823755 [NCBI36]
Chr14:14q11.2-21.2		 pathogenic
GRCh38/hg38 14q11.2(chr14:21919243-22442515)x1 copy number loss See cases [RCV000051207] Chr14:21919243..22442515 [GRCh38]
Chr14:22387418..22911507 [GRCh37]
Chr14:21457258..21981347 [NCBI36]
Chr14:14q11.2		 benign
GRCh38/hg38 14q11.2(chr14:20151149-23442195)x3 copy number gain See cases [RCV000050914] Chr14:20151149..23442195 [GRCh38]
Chr14:20619308..23911404 [GRCh37]
Chr14:19689148..22981244 [NCBI36]
Chr14:14q11.2		 pathogenic
GRCh38/hg38 14q11.2(chr14:22021664-22592708)x1 copy number loss See cases [RCV000053682] Chr14:22021664..22592708 [GRCh38]
Chr14:22489904..23061615 [GRCh37]
Chr14:21559744..22131455 [NCBI36]
Chr14:14q11.2		 benign
GRCh38/hg38 14q11.2-21.1(chr14:20000611-38984415)x3 copy number gain See cases [RCV000053803] Chr14:20000611..38984415 [GRCh38]
Chr14:20468770..39453619 [GRCh37]
Chr14:19538610..38523370 [NCBI36]
Chr14:14q11.2-21.1		 pathogenic
GRCh38/hg38 14q11.2-21.1(chr14:20150949-39746154)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053806]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053806]|See cases [RCV000053806] Chr14:20150949..39746154 [GRCh38]
Chr14:20619108..40215358 [GRCh37]
Chr14:19688948..39285109 [NCBI36]
Chr14:14q11.2-21.1		 pathogenic
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:178
Count of miRNA genes:149
Interacting mature miRNAs:156
Transcripts:ENST00000390452
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
D14S283  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371422,687,545 - 22,687,653UniSTSGRCh37
GRCh371422,687,545 - 22,687,675UniSTSGRCh37
Build 361421,757,385 - 21,757,493RGDNCBI36
Celera142,551,079 - 2,551,187RGD
Celera142,551,079 - 2,551,209UniSTS
Cytogenetic Map14q11UniSTS
Cytogenetic Map14q11.2UniSTS
HuRef142,805,160 - 2,805,304UniSTS
HuRef142,805,160 - 2,805,282UniSTS
Marshfield Genetic Map1413.89RGD
Genethon Genetic Map147.5UniSTS
TNG Radiation Hybrid Map141466.0UniSTS
deCODE Assembly Map1414.7UniSTS
Stanford-G3 RH Map14184.0UniSTS
GeneMap99-GB4 RH Map1414.11UniSTS
GeneMap99-G3 RH Map14184.0UniSTS
D14S920  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371422,892,465 - 22,892,596UniSTSGRCh37
Build 361421,962,305 - 21,962,436RGDNCBI36
Celera142,755,414 - 2,755,545RGD
Cytogenetic Map14q11UniSTS
Cytogenetic Map14q11.2UniSTS
HuRef143,010,724 - 3,010,855UniSTS
TNG Radiation Hybrid Map141555.0UniSTS
Stanford-G3 RH Map14190.0UniSTS
GDB:198183  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371422,649,374 - 22,651,347UniSTSGRCh37
Build 361421,719,214 - 21,721,187RGDNCBI36
Celera142,512,912 - 2,514,885RGD
Cytogenetic Map14q11UniSTS
HuRef142,767,155 - 2,769,131UniSTS
GDB:198184  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371422,652,569 - 22,654,554UniSTSGRCh37
Build 361421,722,409 - 21,724,394RGDNCBI36
Celera142,516,107 - 2,518,092RGD
Cytogenetic Map14q11UniSTS
HuRef142,770,197 - 2,772,182UniSTS
GDB:198186  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371422,613,428 - 22,613,854UniSTSGRCh37
Build 361421,683,268 - 21,683,694RGDNCBI36
Celera142,476,970 - 2,477,396RGD
Cytogenetic Map14q11UniSTS
Cytogenetic Map14q11.2UniSTS
HuRef142,731,205 - 2,731,631UniSTS
GDB:210884  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371422,891,730 - 22,892,049UniSTSGRCh37
Build 361421,961,570 - 21,961,889RGDNCBI36
Celera142,754,677 - 2,754,996RGD
Cytogenetic Map14q11UniSTS
Cytogenetic Map14q11.2UniSTS
HuRef143,009,987 - 3,010,306UniSTS
SHGC-145279  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371422,876,469 - 22,876,803UniSTSGRCh37
Build 361421,946,309 - 21,946,643RGDNCBI36
Celera142,740,005 - 2,740,339RGD
Cytogenetic Map14q11UniSTS
Cytogenetic Map14q11.2UniSTS
HuRef142,994,708 - 2,995,042UniSTS
TNG Radiation Hybrid Map141548.0UniSTS
SHGC-145547  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371422,771,600 - 22,771,905UniSTSGRCh37
Build 361421,841,440 - 21,841,745RGDNCBI36
Celera142,635,127 - 2,635,437RGD
Cytogenetic Map14q11UniSTS
Cytogenetic Map14q11.2UniSTS
HuRef142,889,195 - 2,889,505UniSTS
TNG Radiation Hybrid Map141500.0UniSTS
SHGC-143450  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371422,828,695 - 22,829,043UniSTSGRCh37
Build 361421,898,535 - 21,898,883RGDNCBI36
Celera142,692,222 - 2,692,570RGD
Cytogenetic Map14q11UniSTS
Cytogenetic Map14q11.2UniSTS
HuRef142,946,732 - 2,947,080UniSTS
SHGC-171777  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371422,805,751 - 22,806,072UniSTSGRCh37
Build 361421,875,591 - 21,875,912RGDNCBI36
Celera142,669,279 - 2,669,600RGD
Cytogenetic Map14q11UniSTS
Cytogenetic Map14q11.2UniSTS
HuRef142,923,786 - 2,924,107UniSTS
TNG Radiation Hybrid Map141514.0UniSTS
SHGC-171779  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371422,922,224 - 22,922,500UniSTSGRCh37
Build 361421,992,064 - 21,992,340RGDNCBI36
Celera142,785,175 - 2,785,451RGD
Cytogenetic Map14q11UniSTS
Cytogenetic Map14q11.2UniSTS
HuRef143,040,503 - 3,040,779UniSTS
TNG Radiation Hybrid Map141569.0UniSTS
RH70855  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371422,694,899 - 22,695,104UniSTSGRCh37
Build 361421,764,739 - 21,764,944RGDNCBI36
Celera142,558,432 - 2,558,637RGD
Cytogenetic Map14q11UniSTS
Cytogenetic Map14q11.2UniSTS
HuRef142,812,517 - 2,812,722UniSTS
GeneMap99-GB4 RH Map1412.82UniSTS
G35434  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371422,892,645 - 22,892,855UniSTSGRCh37
Build 361421,962,485 - 21,962,695RGDNCBI36
Celera142,755,594 - 2,755,804RGD
Cytogenetic Map14q11UniSTS
Cytogenetic Map14q11.2UniSTS
HuRef143,010,904 - 3,011,114UniSTS
D14S283  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map14q11-q12UniSTS
Cytogenetic Map14q11.2UniSTS
Cytogenetic Map14q11UniSTS
Marshfield Genetic Map1413.89UniSTS
Genethon Genetic Map147.5UniSTS
deCODE Assembly Map1414.7UniSTS


Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
752 1335 743 649 875 769 1361 1 332 1310 252 892 3225 3101 4 537 445 621 972 80

Sequence


Ensembl Acc Id: ENST00000390452   ⟹   ENSP00000452111
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1422,096,032 - 22,096,619 (+)Ensembl
Ensembl Acc Id: ENST00000621643   ⟹   ENSP00000484940
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1422,096,507 - 22,096,608 (+)Ensembl
Protein Sequences
GenBank Protein A0A1B0GX56 (Get FASTA)   NCBI Sequence Viewer  
  AAA61104 (Get FASTA)   NCBI Sequence Viewer  
  AAB62513 (Get FASTA)   NCBI Sequence Viewer  
  AAB69024 (Get FASTA)   NCBI Sequence Viewer  
  AAK62930 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSP00000452111.1
Ensembl Acc Id: ENSP00000484940   ⟸   ENST00000621643
Ensembl Acc Id: ENSP00000452111   ⟸   ENST00000390452
Protein Domains
Ig-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A1B0GX56-F1-model_v2 AlphaFold A0A1B0GX56 1-115 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:12262 AgrOrtholog
COSMIC TRDV1 COSMIC
Ensembl Genes ENSG00000211804 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000390452.2 UniProtKB/Swiss-Prot
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot
GTEx ENSG00000211804 GTEx
HGNC ID HGNC:12262 ENTREZGENE
Human Proteome Map TRDV1 Human Proteome Map
InterPro Ig-like_dom UniProtKB/Swiss-Prot
  Ig-like_dom_sf UniProtKB/Swiss-Prot
  Ig-like_fold UniProtKB/Swiss-Prot
  Ig_V-set UniProtKB/Swiss-Prot
  TCR_variable_region UniProtKB/Swiss-Prot
NCBI Gene TRDV1 ENTREZGENE
PANTHER IG-LIKE DOMAIN-CONTAINING PROTEIN UniProtKB/Swiss-Prot
  T-CELL RECEPTOR ALPHA CHAIN V REGION UniProtKB/Swiss-Prot
Pfam V-set UniProtKB/Swiss-Prot
PharmGKB PA36942 PharmGKB
PROSITE IG_LIKE UniProtKB/Swiss-Prot
SMART IGv UniProtKB/Swiss-Prot
Superfamily-SCOP SSF48726 UniProtKB/Swiss-Prot
UniProt A0A1B0GX56 ENTREZGENE, UniProtKB/Swiss-Prot