ZNF497 (zinc finger protein 497) - Rat Genome Database

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Gene: ZNF497 (zinc finger protein 497) Homo sapiens
Analyze
Symbol: ZNF497
Name: zinc finger protein 497
RGD ID: 1343501
HGNC Page HGNC:23714
Description: Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: FLJ42722; FLJ44773; zinc finger-like protein
RGD Orthologs
Bonobo
Green Monkey
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381958,354,357 - 58,362,751 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1958,354,357 - 58,362,848 (-)EnsemblGRCh38hg38GRCh38
GRCh371958,865,723 - 58,874,117 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361963,557,537 - 63,565,932 (-)NCBINCBI36Build 36hg18NCBI36
Build 341963,557,536 - 63,565,932NCBI
Celera1955,909,719 - 55,918,113 (-)NCBICelera
Cytogenetic Map19q13.43NCBI
HuRef1955,174,879 - 55,183,369 (-)NCBIHuRef
CHM1_11958,859,654 - 58,868,146 (-)NCBICHM1_1
T2T-CHM13v2.01961,450,773 - 61,459,159 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleus  (IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:14702039   PMID:15489334   PMID:16344560   PMID:21873635   PMID:25416956   PMID:25921289   PMID:32296183   PMID:32814053   PMID:33660365   PMID:33961781   PMID:36949045  


Genomics

Comparative Map Data
ZNF497
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381958,354,357 - 58,362,751 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1958,354,357 - 58,362,848 (-)EnsemblGRCh38hg38GRCh38
GRCh371958,865,723 - 58,874,117 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361963,557,537 - 63,565,932 (-)NCBINCBI36Build 36hg18NCBI36
Build 341963,557,536 - 63,565,932NCBI
Celera1955,909,719 - 55,918,113 (-)NCBICelera
Cytogenetic Map19q13.43NCBI
HuRef1955,174,879 - 55,183,369 (-)NCBIHuRef
CHM1_11958,859,654 - 58,868,146 (-)NCBICHM1_1
T2T-CHM13v2.01961,450,773 - 61,459,159 (-)NCBIT2T-CHM13v2.0
ZNF497
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22064,632,564 - 64,639,980 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11966,420,452 - 66,427,733 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01955,364,806 - 55,372,387 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11964,188,237 - 64,197,014 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1964,190,011 - 64,191,507 (-)Ensemblpanpan1.1panPan2
ZNF497
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1650,631,998 - 50,637,650 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl650,632,086 - 50,633,579 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660453,929,936 - 3,932,471 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in ZNF497
42 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 19q13.33-13.43(chr19:50191219-58535818)x3 copy number gain See cases [RCV000050883] Chr19:50191219..58535818 [GRCh38]
Chr19:50694476..59047185 [GRCh37]
Chr19:55386288..63738997 [NCBI36]
Chr19:19q13.33-13.43		 pathogenic
GRCh38/hg38 19q13.33-13.43(chr19:49907832-58557889)x3 copy number gain See cases [RCV000052925] Chr19:49907832..58557889 [GRCh38]
Chr19:50411089..59069256 [GRCh37]
Chr19:55102901..63761068 [NCBI36]
Chr19:19q13.33-13.43		 pathogenic
GRCh38/hg38 19q13.41-13.43(chr19:51141518-58539965)x3 copy number gain See cases [RCV000052926] Chr19:51141518..58539965 [GRCh38]
Chr19:51644775..59051332 [GRCh37]
Chr19:56336587..63743144 [NCBI36]
Chr19:19q13.41-13.43		 pathogenic
GRCh38/hg38 19q13.43(chr19:56363208-58581203)x3 copy number gain See cases [RCV000052927] Chr19:56363208..58581203 [GRCh38]
Chr19:56874577..59092570 [GRCh37]
Chr19:61566389..63784382 [NCBI36]
Chr19:19q13.43		 pathogenic
GRCh38/hg38 19q13.33-13.43(chr19:47908540-58539965)x3 copy number gain See cases [RCV000052914] Chr19:47908540..58539965 [GRCh38]
Chr19:48411797..59051332 [GRCh37]
Chr19:53103609..63743144 [NCBI36]
Chr19:19q13.33-13.43		 pathogenic
GRCh38/hg38 19q13.33-13.43(chr19:47929575-58572206)x3 copy number gain See cases [RCV000052915] Chr19:47929575..58572206 [GRCh38]
Chr19:48432832..59083573 [GRCh37]
Chr19:53124644..63775385 [NCBI36]
Chr19:19q13.33-13.43		 pathogenic
GRCh38/hg38 19q13.41-13.43(chr19:52612432-58581203)x3 copy number gain See cases [RCV000134174] Chr19:52612432..58581203 [GRCh38]
Chr19:53115685..59092570 [GRCh37]
Chr19:57807497..63784382 [NCBI36]
Chr19:19q13.41-13.43		 pathogenic
GRCh38/hg38 19q13.41-13.43(chr19:52955056-58581203)x3 copy number gain See cases [RCV000134139] Chr19:52955056..58581203 [GRCh38]
Chr19:53458309..59092570 [GRCh37]
Chr19:58150121..63784382 [NCBI36]
Chr19:19q13.41-13.43		 pathogenic
GRCh38/hg38 19q13.33-13.43(chr19:50152520-58581203)x3 copy number gain See cases [RCV000135843] Chr19:50152520..58581203 [GRCh38]
Chr19:50655777..59092570 [GRCh37]
Chr19:55347589..63784382 [NCBI36]
Chr19:19q13.33-13.43		 pathogenic
GRCh38/hg38 19q13.41-13.43(chr19:52143873-58445521)x3 copy number gain See cases [RCV000142008] Chr19:52143873..58445521 [GRCh38]
Chr19:52647126..58956888 [GRCh37]
Chr19:57338938..63648700 [NCBI36]
Chr19:19q13.41-13.43		 pathogenic
GRCh38/hg38 19q13.43(chr19:56353449-58445521)x3 copy number gain See cases [RCV000141900] Chr19:56353449..58445521 [GRCh38]
Chr19:56864818..58956888 [GRCh37]
Chr19:61556630..63648700 [NCBI36]
Chr19:19q13.43		 uncertain significance
GRCh37/hg19 19q13.43(chr19:58458999-58929684)x3 copy number gain See cases [RCV000240566] Chr19:58458999..58929684 [GRCh37]
Chr19:19q13.43		 uncertain significance
GRCh37/hg19 19q13.33-13.43(chr19:50489390-59095359)x3 copy number gain See cases [RCV000445925] Chr19:50489390..59095359 [GRCh37]
Chr19:19q13.33-13.43		 pathogenic
GRCh37/hg19 19q13.42-13.43(chr19:54344821-58956888)x3 copy number gain See cases [RCV000448186] Chr19:54344821..58956888 [GRCh37]
Chr19:19q13.42-13.43		 pathogenic
GRCh37/hg19 19q13.43(chr19:56706500-58956888)x3 copy number gain See cases [RCV000512396] Chr19:56706500..58956888 [GRCh37]
Chr19:19q13.43		 uncertain significance
GRCh37/hg19 19p13.3-q13.43(chr19:260912-58956888)x3 copy number gain See cases [RCV000511289] Chr19:260912..58956888 [GRCh37]
Chr19:19p13.3-q13.43		 pathogenic|uncertain significance
NM_198458.3(ZNF497):c.962A>G (p.Gln321Arg) single nucleotide variant not provided [RCV004696454]|not specified [RCV004307383] Chr19:58356674 [GRCh38]
Chr19:58868040 [GRCh37]
Chr19:19q13.43		 uncertain significance
GRCh37/hg19 19p13.3-q13.43(chr19:260912-58956888) copy number gain See cases [RCV000512296] Chr19:260912..58956888 [GRCh37]
Chr19:19p13.3-q13.43		 pathogenic
GRCh37/hg19 19p13.3-q13.43(chr19:260912-59097160)x3 copy number gain not provided [RCV000752444] Chr19:260912..59097160 [GRCh37]
Chr19:19p13.3-q13.43		 pathogenic
GRCh37/hg19 19p13.3-q13.43(chr19:68029-59110290)x3 copy number gain not provided [RCV000752439] Chr19:68029..59110290 [GRCh37]
Chr19:19p13.3-q13.43		 pathogenic
GRCh37/hg19 19q13.43(chr19:58865587-58879118)x3 copy number gain not provided [RCV000740280] Chr19:58865587..58879118 [GRCh37]
Chr19:19q13.43		 benign
GRCh37/hg19 19q13.33-13.43(chr19:50740074-59097160)x3 copy number gain not provided [RCV000740208] Chr19:50740074..59097160 [GRCh37]
Chr19:19q13.33-13.43		 pathogenic
GRCh37/hg19 19q13.43(chr19:58687912-58946147)x3 copy number gain not provided [RCV001258732] Chr19:58687912..58946147 [GRCh37]
Chr19:19q13.43		 uncertain significance
NM_198458.3(ZNF497):c.1045C>T (p.Arg349Trp) single nucleotide variant not specified [RCV004304572] Chr19:58356591 [GRCh38]
Chr19:58867957 [GRCh37]
Chr19:19q13.43		 uncertain significance
NM_198458.3(ZNF497):c.181C>G (p.Leu61Val) single nucleotide variant not specified [RCV004207775] Chr19:58357455 [GRCh38]
Chr19:58868821 [GRCh37]
Chr19:19q13.43		 uncertain significance
NM_198458.3(ZNF497):c.323G>C (p.Cys108Ser) single nucleotide variant not specified [RCV004162353] Chr19:58357313 [GRCh38]
Chr19:58868679 [GRCh37]
Chr19:19q13.43		 uncertain significance
NM_198458.3(ZNF497):c.722C>T (p.Thr241Met) single nucleotide variant not specified [RCV004223826] Chr19:58356914 [GRCh38]
Chr19:58868280 [GRCh37]
Chr19:19q13.43		 uncertain significance
NM_198458.3(ZNF497):c.578C>T (p.Pro193Leu) single nucleotide variant not specified [RCV004197599] Chr19:58357058 [GRCh38]
Chr19:58868424 [GRCh37]
Chr19:19q13.43		 uncertain significance
NM_198458.3(ZNF497):c.1427G>T (p.Gly476Val) single nucleotide variant not specified [RCV004125241] Chr19:58356209 [GRCh38]
Chr19:58867575 [GRCh37]
Chr19:19q13.43		 uncertain significance
NM_198458.3(ZNF497):c.817C>A (p.Pro273Thr) single nucleotide variant not specified [RCV004184699] Chr19:58356819 [GRCh38]
Chr19:58868185 [GRCh37]
Chr19:19q13.43		 uncertain significance
NM_198458.3(ZNF497):c.1435T>C (p.Phe479Leu) single nucleotide variant not specified [RCV004155882] Chr19:58356201 [GRCh38]
Chr19:58867567 [GRCh37]
Chr19:19q13.43		 uncertain significance
NM_198458.3(ZNF497):c.1318A>G (p.Arg440Gly) single nucleotide variant not specified [RCV004093412] Chr19:58356318 [GRCh38]
Chr19:58867684 [GRCh37]
Chr19:19q13.43		 uncertain significance
NM_198458.3(ZNF497):c.1085A>G (p.Gln362Arg) single nucleotide variant not specified [RCV004163777] Chr19:58356551 [GRCh38]
Chr19:58867917 [GRCh37]
Chr19:19q13.43		 uncertain significance
NM_198458.3(ZNF497):c.1382G>A (p.Arg461Gln) single nucleotide variant not specified [RCV004102892] Chr19:58356254 [GRCh38]
Chr19:58867620 [GRCh37]
Chr19:19q13.43		 uncertain significance
NM_198458.3(ZNF497):c.1476C>A (p.His492Gln) single nucleotide variant not specified [RCV004187834] Chr19:58356160 [GRCh38]
Chr19:58867526 [GRCh37]
Chr19:19q13.43		 uncertain significance
NM_198458.3(ZNF497):c.997G>T (p.Ala333Ser) single nucleotide variant not specified [RCV004147803] Chr19:58356639 [GRCh38]
Chr19:58868005 [GRCh37]
Chr19:19q13.43		 uncertain significance
NM_198458.3(ZNF497):c.334G>A (p.Gly112Ser) single nucleotide variant not specified [RCV004150368] Chr19:58357302 [GRCh38]
Chr19:58868668 [GRCh37]
Chr19:19q13.43		 uncertain significance
NM_198458.3(ZNF497):c.604A>G (p.Ser202Gly) single nucleotide variant not specified [RCV004227753] Chr19:58357032 [GRCh38]
Chr19:58868398 [GRCh37]
Chr19:19q13.43		 uncertain significance
NM_198458.3(ZNF497):c.143C>T (p.Pro48Leu) single nucleotide variant not specified [RCV004225760] Chr19:58357493 [GRCh38]
Chr19:58868859 [GRCh37]
Chr19:19q13.43		 uncertain significance
NM_198458.3(ZNF497):c.1226C>A (p.Thr409Lys) single nucleotide variant not specified [RCV004190291] Chr19:58356410 [GRCh38]
Chr19:58867776 [GRCh37]
Chr19:19q13.43		 uncertain significance
NM_198458.3(ZNF497):c.1246T>A (p.Cys416Ser) single nucleotide variant not specified [RCV004180591] Chr19:58356390 [GRCh38]
Chr19:58867756 [GRCh37]
Chr19:19q13.43		 uncertain significance
NM_198458.3(ZNF497):c.264C>G (p.Ser88Arg) single nucleotide variant not specified [RCV004089949] Chr19:58357372 [GRCh38]
Chr19:58868738 [GRCh37]
Chr19:19q13.43		 uncertain significance
NM_198458.3(ZNF497):c.641G>T (p.Gly214Val) single nucleotide variant not specified [RCV004294085] Chr19:58356995 [GRCh38]
Chr19:58868361 [GRCh37]
Chr19:19q13.43		 uncertain significance
NM_198458.3(ZNF497):c.93G>C (p.Glu31Asp) single nucleotide variant not specified [RCV004285152] Chr19:58357543 [GRCh38]
Chr19:58868909 [GRCh37]
Chr19:19q13.43		 uncertain significance
NM_198458.3(ZNF497):c.637A>G (p.Thr213Ala) single nucleotide variant not specified [RCV004265642] Chr19:58356999 [GRCh38]
Chr19:58868365 [GRCh37]
Chr19:19q13.43		 uncertain significance
NM_198458.3(ZNF497):c.709C>T (p.Arg237Trp) single nucleotide variant not specified [RCV004265643] Chr19:58356927 [GRCh38]
Chr19:58868293 [GRCh37]
Chr19:19q13.43		 uncertain significance
NM_198458.3(ZNF497):c.232G>A (p.Asp78Asn) single nucleotide variant not specified [RCV004353541] Chr19:58357404 [GRCh38]
Chr19:58868770 [GRCh37]
Chr19:19q13.43		 uncertain significance
NM_198458.3(ZNF497):c.220C>G (p.Leu74Val) single nucleotide variant not specified [RCV004358699] Chr19:58357416 [GRCh38]
Chr19:58868782 [GRCh37]
Chr19:19q13.43		 uncertain significance
NM_198458.3(ZNF497):c.929C>G (p.Ala310Gly) single nucleotide variant not specified [RCV004353510] Chr19:58356707 [GRCh38]
Chr19:58868073 [GRCh37]
Chr19:19q13.43		 uncertain significance
NM_198458.3(ZNF497):c.263G>A (p.Ser88Asn) single nucleotide variant not specified [RCV004363835] Chr19:58357373 [GRCh38]
Chr19:58868739 [GRCh37]
Chr19:19q13.43		 uncertain significance
NM_198458.3(ZNF497):c.1051G>A (p.Val351Met) single nucleotide variant not specified [RCV004492063] Chr19:58356585 [GRCh38]
Chr19:58867951 [GRCh37]
Chr19:19q13.43		 uncertain significance
NM_198458.3(ZNF497):c.114G>T (p.Trp38Cys) single nucleotide variant not specified [RCV004492065] Chr19:58357522 [GRCh38]
Chr19:58868888 [GRCh37]
Chr19:19q13.43		 uncertain significance
NM_198458.3(ZNF497):c.1189G>A (p.Gly397Ser) single nucleotide variant not specified [RCV004492066] Chr19:58356447 [GRCh38]
Chr19:58867813 [GRCh37]
Chr19:19q13.43		 uncertain significance
NM_198458.3(ZNF497):c.118G>A (p.Ala40Thr) single nucleotide variant not specified [RCV004492067] Chr19:58357518 [GRCh38]
Chr19:58868884 [GRCh37]
Chr19:19q13.43		 uncertain significance
NM_198458.3(ZNF497):c.1466A>G (p.Gln489Arg) single nucleotide variant not specified [RCV004492068] Chr19:58356170 [GRCh38]
Chr19:58867536 [GRCh37]
Chr19:19q13.43		 uncertain significance
NM_198458.3(ZNF497):c.182T>C (p.Leu61Pro) single nucleotide variant not specified [RCV004492069] Chr19:58357454 [GRCh38]
Chr19:58868820 [GRCh37]
Chr19:19q13.43		 uncertain significance
NM_198458.3(ZNF497):c.229G>A (p.Ala77Thr) single nucleotide variant not specified [RCV004492071] Chr19:58357407 [GRCh38]
Chr19:58868773 [GRCh37]
Chr19:19q13.43		 uncertain significance
NM_198458.3(ZNF497):c.505A>G (p.Lys169Glu) single nucleotide variant not specified [RCV004492073] Chr19:58357131 [GRCh38]
Chr19:58868497 [GRCh37]
Chr19:19q13.43		 uncertain significance
NM_198458.3(ZNF497):c.226C>A (p.Pro76Thr) single nucleotide variant not specified [RCV004492070] Chr19:58357410 [GRCh38]
Chr19:58868776 [GRCh37]
Chr19:19q13.43		 uncertain significance
NM_198458.3(ZNF497):c.293C>T (p.Ser98Leu) single nucleotide variant not specified [RCV004492072] Chr19:58357343 [GRCh38]
Chr19:58868709 [GRCh37]
Chr19:19q13.43		 uncertain significance
NM_198458.3(ZNF497):c.684C>G (p.Ser228Arg) single nucleotide variant not specified [RCV004492075] Chr19:58356952 [GRCh38]
Chr19:58868318 [GRCh37]
Chr19:19q13.43		 uncertain significance
NM_198458.3(ZNF497):c.1126C>T (p.His376Tyr) single nucleotide variant not specified [RCV004492064] Chr19:58356510 [GRCh38]
Chr19:58867876 [GRCh37]
Chr19:19q13.43		 uncertain significance
NM_198458.3(ZNF497):c.571C>T (p.Arg191Cys) single nucleotide variant not specified [RCV004492074] Chr19:58357065 [GRCh38]
Chr19:58868431 [GRCh37]
Chr19:19q13.43		 uncertain significance
NM_198458.3(ZNF497):c.734C>T (p.Pro245Leu) single nucleotide variant not specified [RCV004492076] Chr19:58356902 [GRCh38]
Chr19:58868268 [GRCh37]
Chr19:19q13.43		 uncertain significance
NM_198458.3(ZNF497):c.1114A>T (p.Asn372Tyr) single nucleotide variant not specified [RCV004605363] Chr19:58356522 [GRCh38]
Chr19:58867888 [GRCh37]
Chr19:19q13.43		 uncertain significance
NM_198458.3(ZNF497):c.929C>T (p.Ala310Val) single nucleotide variant not specified [RCV004605362] Chr19:58356707 [GRCh38]
Chr19:58868073 [GRCh37]
Chr19:19q13.43		 likely benign
NM_198458.3(ZNF497):c.1322C>T (p.Pro441Leu) single nucleotide variant not specified [RCV004605365] Chr19:58356314 [GRCh38]
Chr19:58867680 [GRCh37]
Chr19:19q13.43		 uncertain significance
NM_198458.3(ZNF497):c.1192A>C (p.Ser398Arg) single nucleotide variant not specified [RCV004605364] Chr19:58356444 [GRCh38]
Chr19:58867810 [GRCh37]
Chr19:19q13.43		 uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1698
Count of miRNA genes:851
Interacting mature miRNAs:1011
Transcripts:ENST00000311044, ENST00000425453, ENST00000595763
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
G59506  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371958,866,408 - 58,866,510UniSTSGRCh37
Build 361963,558,220 - 63,558,322RGDNCBI36
Celera1955,910,402 - 55,910,504RGD
Cytogenetic Map19q13.43UniSTS
Cytogenetic Map19q13.4UniSTS
HuRef1955,175,564 - 55,175,666UniSTS
TNG Radiation Hybrid Map1923295.0UniSTS
D19S238E  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371958,868,295 - 58,868,401UniSTSGRCh37
Build 361963,560,107 - 63,560,213RGDNCBI36
Celera1955,912,289 - 55,912,395RGD
Cytogenetic Map19q13.43UniSTS
HuRef1955,177,451 - 55,177,557UniSTS
RH65092  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371958,865,752 - 58,865,964UniSTSGRCh37
Build 361963,557,564 - 63,557,776RGDNCBI36
Celera1955,909,746 - 55,909,958RGD
Cytogenetic Map19q13.43UniSTS
Cytogenetic Map19q13.4UniSTS
HuRef1955,174,908 - 55,175,120UniSTS
GeneMap99-GB4 RH Map19293.71UniSTS
WI-16009  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371958,866,360 - 58,866,510UniSTSGRCh37
Build 361963,558,172 - 63,558,322RGDNCBI36
Celera1955,910,354 - 55,910,504RGD
Cytogenetic Map19q13.43UniSTS
Cytogenetic Map19q13.4UniSTS
HuRef1955,175,516 - 55,175,666UniSTS
GeneMap99-GB4 RH Map19290.96UniSTS
Whitehead-RH Map19381.5UniSTS
NCBI RH Map19600.5UniSTS


Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
pharyngeal arch
renal system
reproductive system
respiratory system
sensory system
visual system
1204 2434 2787 2248 4963 1724 2349 5 622 1924 464 2267 7259 6432 52 3728 1 849 1741 1615 173 1

Sequence


Ensembl Acc Id: ENST00000311044   ⟹   ENSP00000311183
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1958,354,357 - 58,362,751 (-)Ensembl
Ensembl Acc Id: ENST00000425453   ⟹   ENSP00000402815
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1958,355,561 - 58,362,848 (-)Ensembl
Ensembl Acc Id: ENST00000595763   ⟹   ENSP00000471650
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1958,357,439 - 58,362,825 (-)Ensembl
RefSeq Acc Id: NM_001207009   ⟹   NP_001193938
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381958,354,357 - 58,362,751 (-)NCBI
GRCh371958,865,723 - 58,874,214 (-)ENTREZGENE
HuRef1955,174,879 - 55,183,369 (-)ENTREZGENE
CHM1_11958,859,654 - 58,868,146 (-)NCBI
T2T-CHM13v2.01961,450,773 - 61,459,159 (-)NCBI
Sequence:
RefSeq Acc Id: NM_198458   ⟹   NP_940860
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381958,354,357 - 58,362,751 (-)NCBI
GRCh371958,865,723 - 58,874,214 (-)ENTREZGENE
Build 361963,557,537 - 63,565,932 (-)NCBI Archive
Celera1955,909,719 - 55,918,113 (-)RGD
HuRef1955,174,879 - 55,183,369 (-)ENTREZGENE
CHM1_11958,859,654 - 58,868,146 (-)NCBI
T2T-CHM13v2.01961,450,773 - 61,459,159 (-)NCBI
Sequence:
RefSeq Acc Id: NP_940860   ⟸   NM_198458
- UniProtKB: Q6ZTD2 (UniProtKB/Swiss-Prot),   Q0VF48 (UniProtKB/Swiss-Prot),   Q05AG8 (UniProtKB/Swiss-Prot),   Q9UIA8 (UniProtKB/Swiss-Prot),   Q6ZNH5 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001193938   ⟸   NM_001207009
- UniProtKB: Q6ZTD2 (UniProtKB/Swiss-Prot),   Q0VF48 (UniProtKB/Swiss-Prot),   Q05AG8 (UniProtKB/Swiss-Prot),   Q9UIA8 (UniProtKB/Swiss-Prot),   Q6ZNH5 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSP00000471650   ⟸   ENST00000595763
Ensembl Acc Id: ENSP00000402815   ⟸   ENST00000425453
Ensembl Acc Id: ENSP00000311183   ⟸   ENST00000311044

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6ZNH5-F1-model_v2 AlphaFold Q6ZNH5 1-498 view protein structure

Promoters
RGD ID:13205989
Promoter ID:EPDNEW_H26575
Type:initiation region
Name:ZNF497_1
Description:zinc finger protein 497
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H26576  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381958,362,751 - 58,362,811EPDNEW
RGD ID:13205991
Promoter ID:EPDNEW_H26576
Type:single initiation site
Name:ZNF497_2
Description:zinc finger protein 497
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H26575  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381958,364,441 - 58,364,501EPDNEW
RGD ID:6795470
Promoter ID:HG_KWN:31231
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour
Transcripts:ENST00000391697,   UC010EUP.1
Position:
Human AssemblyChrPosition (strand)Source
Build 361963,559,364 - 63,559,864 (-)MPROMDB
RGD ID:6795661
Promoter ID:HG_KWN:31233
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Jurkat
Transcripts:NM_198458,   UC002QSF.1,   UC002QSI.1
Position:
Human AssemblyChrPosition (strand)Source
Build 361963,565,636 - 63,566,136 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:23714 AgrOrtholog
COSMIC ZNF497 COSMIC
Ensembl Genes ENSG00000174586 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000311044 ENTREZGENE
  ENST00000311044.8 UniProtKB/Swiss-Prot
  ENST00000425453 ENTREZGENE
  ENST00000425453.3 UniProtKB/Swiss-Prot
  ENST00000595763.1 UniProtKB/TrEMBL
Gene3D-CATH Classic Zinc Finger UniProtKB/Swiss-Prot
GTEx ENSG00000174586 GTEx
HGNC ID HGNC:23714 ENTREZGENE
Human Proteome Map ZNF497 Human Proteome Map
InterPro Zinc_finger UniProtKB/Swiss-Prot
  Znf_C2H2_sf UniProtKB/Swiss-Prot
  Znf_C2H2_type UniProtKB/Swiss-Prot
KEGG Report hsa:162968 UniProtKB/Swiss-Prot
NCBI Gene 162968 ENTREZGENE
PANTHER PR DOMAIN ZINC FINGER PROTEIN UniProtKB/Swiss-Prot
  ZINC FINGER PROTEIN 711 UniProtKB/Swiss-Prot
Pfam zf-C2H2 UniProtKB/Swiss-Prot
PharmGKB PA134994387 PharmGKB
PROSITE ZINC_FINGER_C2H2_1 UniProtKB/Swiss-Prot
  ZINC_FINGER_C2H2_2 UniProtKB/Swiss-Prot
SMART ZnF_C2H2 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF57667 UniProtKB/Swiss-Prot
UniProt M0R159_HUMAN UniProtKB/TrEMBL
  Q05AG8 ENTREZGENE
  Q0VF48 ENTREZGENE
  Q6ZNH5 ENTREZGENE
  Q6ZTD2 ENTREZGENE
  Q9UIA8 ENTREZGENE
  ZN497_HUMAN UniProtKB/Swiss-Prot
UniProt Secondary Q05AG8 UniProtKB/Swiss-Prot
  Q0VF48 UniProtKB/Swiss-Prot
  Q6ZTD2 UniProtKB/Swiss-Prot
  Q9UIA8 UniProtKB/Swiss-Prot