Efcab10 (EF-hand calcium binding domain 10) - Rat Genome Database

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Gene: Efcab10 (EF-hand calcium binding domain 10) Mus musculus
Analyze
Symbol: Efcab10
Name: EF-hand calcium binding domain 10
RGD ID: 1317431
MGI Page MGI
Description: Predicted to enable calcium ion binding activity. Is expressed in lung. Orthologous to human EFCAB10 (EF-hand calcium binding domain 10).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 4930504H06Rik; EF-hand calcium-binding domain-containing protein 10
RGD Orthologs
Human
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391233,444,824 - 33,451,268 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1233,444,853 - 33,451,266 (+)EnsemblGRCm39 Ensembl
GRCm381233,394,825 - 33,401,269 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1233,394,854 - 33,401,267 (+)EnsemblGRCm38mm10GRCm38
MGSCv371234,079,719 - 34,086,134 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361233,980,101 - 33,986,516 (+)NCBIMGSCv36mm8
Celera1234,839,250 - 34,845,770 (+)NCBICelera
Cytogenetic Map12A3NCBI
cM Map1214.34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:11042159   PMID:11076861   PMID:12477932   PMID:14610273   PMID:16141072   PMID:16141073   PMID:17971504   PMID:27914912  


Genomics

Comparative Map Data
Efcab10
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391233,444,824 - 33,451,268 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1233,444,853 - 33,451,266 (+)EnsemblGRCm39 Ensembl
GRCm381233,394,825 - 33,401,269 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1233,394,854 - 33,401,267 (+)EnsemblGRCm38mm10GRCm38
MGSCv371234,079,719 - 34,086,134 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361233,980,101 - 33,986,516 (+)NCBIMGSCv36mm8
Celera1234,839,250 - 34,845,770 (+)NCBICelera
Cytogenetic Map12A3NCBI
cM Map1214.34NCBI
EFCAB10
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387105,565,124 - 105,581,493 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7105,565,120 - 105,600,875 (-)EnsemblGRCh38hg38GRCh38
GRCh377105,205,571 - 105,221,940 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 367104,992,689 - 105,009,177 (-)NCBINCBI36Build 36hg18NCBI36
Celera7100,010,699 - 100,027,094 (-)NCBICelera
Cytogenetic Map7q22.3NCBI
HuRef799,563,858 - 99,580,241 (-)NCBIHuRef
CHM1_17105,138,892 - 105,155,283 (-)NCBICHM1_1
T2T-CHM13v2.07106,879,330 - 106,895,701 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27104,566,137 - 104,582,536 (-)NCBI
Efcab10
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8655,731,902 - 55,738,821 (+)NCBIGRCr8
mRatBN7.2650,004,479 - 50,011,398 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl650,004,479 - 50,011,398 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx650,309,027 - 50,315,996 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0650,623,962 - 50,630,931 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0650,062,942 - 50,069,893 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0652,702,304 - 52,709,223 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl652,702,544 - 52,709,223 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0662,323,316 - 62,330,235 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4651,741,044 - 51,747,963 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1651,744,407 - 51,751,089 (+)NCBI
Celera649,194,412 - 49,201,339 (+)NCBICelera
Cytogenetic Map6q16NCBI
EFCAB10
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26142,415,837 - 142,432,528 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17190,685,805 - 190,702,289 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0797,556,418 - 97,571,987 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17110,285,036 - 110,301,514 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7110,285,036 - 110,301,501 (-)Ensemblpanpan1.1panPan2
EFCAB10
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11814,833,401 - 14,844,081 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1814,833,472 - 14,845,956 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1814,484,482 - 14,495,115 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01815,135,732 - 15,146,558 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1815,135,758 - 15,148,449 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11814,921,898 - 14,932,520 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01814,844,769 - 14,855,466 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01815,124,870 - 15,135,501 (+)NCBIUU_Cfam_GSD_1.0
Efcab10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511857,181,530 - 57,188,497 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647918,305,334 - 18,314,449 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647918,305,335 - 18,312,252 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PUS7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9105,419,056 - 105,445,682 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19105,424,408 - 105,445,667 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29116,193,298 - 116,213,600 (-)NCBISscrofa10.2Sscrofa10.2susScr3
EFCAB10
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12174,490,873 - 74,505,942 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604229,411,131 - 29,424,270 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in Efcab10
259 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:103
Count of miRNA genes:92
Interacting mature miRNAs:94
Transcripts:ENSMUST00000020878
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301723Fcsa7_mfemoral cross-sectional area 7 (mouse)Not determined12949100443491112Mouse
15039339Nmrs29_mNAFLD-associated magnetic resonance shift 29 (mouse)121782585251825852Mouse
1302172Skts5_mskin tumor susceptibility 5 (mouse)Not determined122214886656149016Mouse
1300636Gct2_mgranulosa cell tumorigenesis 2 (mouse)Not determined122916068563160884Mouse
10043977Obq34_mobesity QTL 34 (mouse)Not determined121514733149147331Mouse
10043848Hdlq90_mHDL QTL 90 (mouse)Not determined121783993951840081Mouse
1558978Cplaq10_mcircadian period of locomotor activity 10 (mouse)Not determined121534102679040364Mouse
1301574Lmblgq5_mlimb length QTL 5 (mouse)Not determined121759644780956883Mouse
1300870Ath18_matherosclerosis 18 (mouse)Not determined121825996652260067Mouse
13207568Tcq14_mtotal cholesterol QTL 14 (mouse)121166000197176774Mouse
27226753Femd7_mfemur midshaft diameter 7, 10 week (mouse)12955000084146774Mouse
14747008Mancz10_mmandible centroid size 10 (mouse)122986352263863522Mouse
4141660Nbwa1_mNZB and NZW autoimmunity 1 (mouse)Not determined1234013434340302Mouse
4142234Tmc1m3_mTmc1 modifier 3 (mouse)Not determined12541844077031203Mouse
13524843Ppiq8_mprepulse inhibition QTL 8 (mouse)121104319450945796Mouse
26884413Bzwq9_mbi-zygomatic width QTL 9, 10 week (mouse)121615000147746783Mouse
13524839Ppiq10_mprepulse inhibition QTL 10 (mouse)121304319554945798Mouse
4141843Moen3_mmodifier of engrailed QTL 3 (mouse)Not determined122980158463801733Mouse
13208568Bmiq11_mbody mass index QTL 11 (mouse)12805000040049999Mouse
4141516slwr_mslowlearner (mouse)Not determined1239247546392614Mouse
1301989Hdlq18_mHDL QTL 18 (mouse)Not determined122916068563160884Mouse
1301163Eae16_msusceptibility to experimental allergic encephalomyelitis 16 (mouse)Not determined12772315841723301Mouse
12904956Edlmmq10_mextensor digitorum longus muscle mass QTL 10 (mouse)121973983353739833Mouse
14746972Manh72_mmandible shape 72 (mouse)121061528144615281Mouse
1301037Cd4ts5_mCD4 T cell subset 5 (mouse)Not determined12835244442352581Mouse
10401249Bglu15_mblood glucose level 15 (mouse)Not determined121062064244620809Mouse


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000020878   ⟹   ENSMUSP00000020878
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1233,444,853 - 33,451,266 (+)Ensembl
GRCm38.p6 Ensembl1233,394,854 - 33,401,267 (+)Ensembl
RefSeq Acc Id: NM_029152   ⟹   NP_083428
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391233,444,853 - 33,451,268 (+)NCBI
GRCm381233,394,854 - 33,401,269 (+)ENTREZGENE
MGSCv371234,079,719 - 34,086,134 (+)RGD
Celera1234,839,250 - 34,845,770 (+)RGD
cM Map12 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_030246964   ⟹   XP_030102824
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391233,444,824 - 33,451,268 (+)NCBI
GRCm381233,394,825 - 33,401,269 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_083428 (Get FASTA)   NCBI Sequence Viewer  
  XP_030102824 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein BAB29935 (Get FASTA)   NCBI Sequence Viewer  
  EDL36874 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000020878
  ENSMUSP00000020878.7
GenBank Protein Q9D581 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_083428   ⟸   NM_029152
- UniProtKB: Q9D581 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_030102824   ⟸   XM_030246964
- Peptide Label: isoform X1
Ensembl Acc Id: ENSMUSP00000020878   ⟸   ENSMUST00000020878
Protein Domains
EF-hand

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9D581-F1-model_v2 AlphaFold Q9D581 1-132 view protein structure

Promoters
RGD ID:8678128
Promoter ID:EPDNEW_M17095
Type:initiation region
Name:Efcab10_1
Description:Mus musculus EF-hand calcium binding domain 10 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381233,394,819 - 33,394,879EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1922290 AgrOrtholog
Ensembl Genes ENSMUSG00000020562 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000020878 ENTREZGENE
  ENSMUST00000020878.8 UniProtKB/Swiss-Prot
InterPro DD_EFCAB10 UniProtKB/Swiss-Prot
  EF-hand-dom_pair UniProtKB/Swiss-Prot
  EF_hand_dom UniProtKB/Swiss-Prot
  EFC10 UniProtKB/Swiss-Prot
KEGG Report mmu:75040 UniProtKB/Swiss-Prot
MGD MGI:1922290 ENTREZGENE
NCBI Gene 75040 ENTREZGENE
PANTHER EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 10 UniProtKB/Swiss-Prot
  PTHR21847 UniProtKB/Swiss-Prot
PhenoGen Efcab10 PhenoGen
PROSITE EF_HAND_2 UniProtKB/Swiss-Prot
Superfamily-SCOP Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit UniProtKB/Swiss-Prot
  SSF47473 UniProtKB/Swiss-Prot
UniProt EFC10_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE