Slc2a10 (solute carrier family 2 (facilitated glucose transporter), member 10) - Rat Genome Database

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Gene: Slc2a10 (solute carrier family 2 (facilitated glucose transporter), member 10) Mus musculus
Analyze
Symbol: Slc2a10
Name: solute carrier family 2 (facilitated glucose transporter), member 10
RGD ID: 1315234
MGI Page MGI
Description: Predicted to enable D-glucose transmembrane transporter activity; dehydroascorbic acid transmembrane transporter activity; and symporter activity. Predicted to be involved in D-glucose import across plasma membrane; circulatory system development; and dehydroascorbic acid transport. Predicted to act upstream of or within several processes, including cell redox homeostasis; regulation of macromolecule biosynthetic process; and regulation of transforming growth factor beta receptor signaling pathway. Predicted to be located in cytosol and perinuclear region of cytoplasm. Predicted to be active in plasma membrane. Is expressed in nervous system. Human ortholog(s) of this gene implicated in arterial tortuosity syndrome. Orthologous to human SLC2A10 (solute carrier family 2 member 10).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: AA450473; glucose transporter type 10; GLUT-10; Glut1; Glut10; solute carrier family 2, facilitated glucose transporter member 10
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392165,345,817 - 165,361,837 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2165,345,707 - 165,361,837 (+)EnsemblGRCm39 Ensembl
GRCm382165,503,897 - 165,519,917 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2165,503,787 - 165,519,917 (+)EnsemblGRCm38mm10GRCm38
MGSCv372165,329,478 - 165,345,411 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362165,185,038 - 165,211,116 (+)NCBIMGSCv36mm8
Celera2171,444,991 - 171,459,433 (+)NCBICelera
Cytogenetic Map2H3NCBI
cM Map285.66NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. MGDs mouse GO annotations MGD data from the GO Consortium
2. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
3. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
4. Mouse MP Annotation Import Pipeline RGD automated import pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:9880682   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11592815   PMID:12477932   PMID:12890477   PMID:14681479   PMID:16141072   PMID:16141073   PMID:18693279  
PMID:19028722   PMID:20639396   PMID:21267068   PMID:21873635   PMID:24227476   PMID:25391964   PMID:29149261   PMID:30013986   PMID:32307537   PMID:32453789   PMID:35478964   PMID:37170065  
PMID:37220836   PMID:38355793  


Genomics

Comparative Map Data
Slc2a10
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392165,345,817 - 165,361,837 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2165,345,707 - 165,361,837 (+)EnsemblGRCm39 Ensembl
GRCm382165,503,897 - 165,519,917 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2165,503,787 - 165,519,917 (+)EnsemblGRCm38mm10GRCm38
MGSCv372165,329,478 - 165,345,411 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362165,185,038 - 165,211,116 (+)NCBIMGSCv36mm8
Celera2171,444,991 - 171,459,433 (+)NCBICelera
Cytogenetic Map2H3NCBI
cM Map285.66NCBI
SLC2A10
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382046,708,320 - 46,736,347 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2046,709,649 - 46,736,347 (+)EnsemblGRCh38hg38GRCh38
GRCh372045,338,288 - 45,364,986 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362044,771,686 - 44,798,393 (+)NCBINCBI36Build 36hg18NCBI36
Build 342044,771,685 - 44,798,390NCBI
Celera2042,049,759 - 42,076,462 (+)NCBICelera
Cytogenetic Map20q13.12NCBI
HuRef2042,079,514 - 42,106,227 (+)NCBIHuRef
CHM1_12045,241,287 - 45,267,979 (+)NCBICHM1_1
T2T-CHM13v2.02048,444,561 - 48,472,618 (+)NCBIT2T-CHM13v2.0
Slc2a10
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83174,659,683 - 174,671,978 (+)NCBIGRCr8
mRatBN7.23154,240,395 - 154,252,690 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3154,240,391 - 154,252,690 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3158,044,192 - 158,056,501 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03166,543,172 - 166,555,481 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03164,284,813 - 164,297,122 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03162,182,156 - 162,194,610 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3162,181,974 - 162,194,804 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03168,364,925 - 168,377,379 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43156,560,451 - 156,572,777 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13156,448,574 - 156,476,839 (+)NCBI
Celera3152,832,517 - 152,844,696 (+)NCBICelera
Cytogenetic Map3q42NCBI
Slc2a10
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544510,709,681 - 10,722,264 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544510,708,147 - 10,722,109 (-)NCBIChiLan1.0ChiLan1.0
SLC2A10
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22152,446,829 - 52,471,342 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12052,439,932 - 52,464,480 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02043,043,801 - 43,068,304 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12044,128,837 - 44,153,154 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2044,128,837 - 44,153,148 (+)Ensemblpanpan1.1panPan2
SLC2A10
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12433,905,099 - 33,920,604 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2433,905,203 - 33,919,454 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2433,365,346 - 33,380,379 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02434,613,963 - 34,628,991 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2434,614,019 - 34,628,991 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12433,870,705 - 33,885,725 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02433,987,615 - 34,002,642 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02434,526,597 - 34,541,658 (+)NCBIUU_Cfam_GSD_1.0
Slc2a10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640191,037,110 - 191,050,617 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365146,493,512 - 6,497,063 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365146,490,728 - 6,504,152 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC2A10
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1748,824,414 - 48,843,201 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11748,824,054 - 48,842,811 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21754,526,449 - 54,533,934 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SLC2A10
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1217,160,692 - 17,185,875 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605065,803,530 - 65,828,497 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slc2a10
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247907,966,694 - 7,982,367 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247907,967,398 - 7,982,312 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:795
Count of miRNA genes:483
Interacting mature miRNAs:576
Transcripts:ENSMUST00000029196, ENSMUST00000148463
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301907Rends_mrenal disease susceptibility (mouse)Not determined2135699221169699361Mouse
1300688Nidd2k_mNidd2 on KK-A (mouse)Not determined2158078337178442452Mouse
1558867Gnf3_mgrowth and fatness 3 (mouse)Not determined2152699221169117924Mouse
1301783Bhr1_mbronchial hyperresponsiveness 1 (mouse)Not determined2142593476178442452Mouse
12790983Bwq12_mbody weight QTL 12 (mouse)2148238204181755017Mouse
11038701Ltpr2e_mLeishmania tropica response 2e (mouse)2150212221181755017Mouse
11038702Ltpr2_mLeishmania tropica response 2 (mouse)2103095716167212356Mouse
1301019Bmd6_mbone mineral density 6 (mouse)Not determined2151778297181755017Mouse
1558939Gnf1_mgrowth and fatness 1 (mouse)Not determined2143773445169117924Mouse
4142450Lmr16_mleishmaniasis resistance 16 (mouse)Not determined2150212221181755017Mouse
1301085Lrnx10_mlearning-contextual 10 (mouse)Not determined2150212221181755017Mouse
11353826Bdln10_mbody length 10 (mouse)2140441482174441482Mouse
1300867Lore2_mloss of righting induced by ethanol 2 (mouse)Not determined2144515861180896594Mouse
1558917Gct8_mgranulosa cell tumorigenesis 8 (mouse)Not determined2149236907181755017Mouse
1300806Aod4_mautoimmune ovarian dysgenesis 4 (mouse)Not determined2145228719179228841Mouse
12910800Pwgrq3_mpre-weaning growth rate QTL 3 (mouse)2160611165169794802Mouse
1300676Prdt2_mprion disease incubation time 2 (mouse)Not determined2164515154181755017Mouse
1558991Tailq4_mtail length QTL 4 (mouse)Not determined2162736926178442452Mouse
1301961Bts1_mbladder tumor susceptibility 1 (mouse)Not determined2132024159166024330Mouse
14747002Mancz3_mmandible centroid size 3 (mouse)2152329820181755017Mouse
1300751Bdt1_mbone density traits 1 (mouse)Not determined2149988902181755017Mouse
1300622Cfld1_mcystic fibrosis lung disease 1 (mouse)Not determined2155823920181755017Mouse
12910810Pwbwq2_mpre-weaning body weight QTL 2 (mouse)2160611165169794802Mouse
1302003Sluc17_msusceptibility to lung cancer 17 (mouse)Not determined2162433493181755017Mouse
1301618Bglu1_mblood glucose level 1 (mouse)Not determined2117942930174324863Mouse
27226749Femd10_mfemur midshaft diameter 10, 16 week (mouse)2124441920168241920Mouse
10054066Bwq9_mbody weight QTL 9 (mouse)Not determined2135699221169699361Mouse
10043956Gnf5_mgrowth and fatness 5 (mouse)Not determined2135699221169699361Mouse
1302013Tbbmd3_mtotal body bone mineral density 3 (mouse)Not determined2145196949179197085Mouse
1357435Epfq2_mepididymal fat pad weight QTL 2 (mouse)Not determined2162736926178442452Mouse
5491196Mobq6_mmultigenic obesity QTL 6 (mouse)Not determined285724269180896594Mouse
12801456Intmrm1_mintima/media ratio modifier 1 (mouse)2142428347176428450Mouse
1357537Lith12_mlithogenic gene 12 (mouse)Not determined2156196464181755017Mouse
12801461Intim1_mintima modifier 1 (mouse)2142428347176428450Mouse
11049566Lmr28e_mleishmaniasis resistance 28e (mouse)2133144911167145058Mouse
1301348Alcp5_malcohol preference locus 5 (mouse)Not determined2163486407181755017Mouse
11049567Lmr28f_mleishmaniasis resistance 28f (mouse)2133144911167145058Mouse
1357484Bsbob_mBSB obesity (mouse)Not determined2143773445165665019Mouse
4141703Chlq13_mcirculating hormone level QTL 13 (mouse)Not determined2135699221169699361Mouse
11341717Rvfs1_mRift Valley fever susceptibility 1 (mouse)2135432544173449616Mouse
1301865Hdlq19_mHDL QTL 19 (mouse)Not determined2145518775179518926Mouse
4142211Nilac3_mnicotine induced locomotor activity 3 (mouse)Not determined2148664893181755017Mouse
12910520Scgq3_mspontaneous crescentic glomerulonephritis QTL 3 (mouse)2151709273174389124Mouse
1300846Pbwg11_mpostnatal body weight growth 11 (mouse)Not determined2138966600172966729Mouse
1301677Alcp6_malcohol preference locus 6 (mouse)Not determined2163486407181755017Mouse

Markers in Region
D2Mit289  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm382165,519,743 - 165,519,871UniSTSGRCm38
MGSCv372165,345,243 - 165,345,371UniSTSGRCm37
Celera2171,459,265 - 171,459,393UniSTS
Cytogenetic Map2H3UniSTS
cM Map298.0UniSTS
Whitehead Genetic283.1UniSTS
Whitehead/MRC_RH21888.07UniSTS
Slc2a10  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map2H3UniSTS
cM Map285.66UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000029196   ⟹   ENSMUSP00000029196
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2165,345,707 - 165,361,837 (+)Ensembl
GRCm38.p6 Ensembl2165,503,787 - 165,519,917 (+)Ensembl
Ensembl Acc Id: ENSMUST00000148463
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2165,350,701 - 165,356,697 (+)Ensembl
GRCm38.p6 Ensembl2165,508,781 - 165,514,777 (+)Ensembl
RefSeq Acc Id: NM_130451   ⟹   NP_569718
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392165,345,817 - 165,361,837 (+)NCBI
GRCm382165,503,897 - 165,519,917 (+)NCBI
MGSCv372165,329,478 - 165,345,411 (+)RGD
Celera2171,444,910 - 171,459,439 (+)NCBI
cM Map2 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_569718 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI37918 (Get FASTA)   NCBI Sequence Viewer  
  AAI37921 (Get FASTA)   NCBI Sequence Viewer  
  AAK38739 (Get FASTA)   NCBI Sequence Viewer  
  BAC34861 (Get FASTA)   NCBI Sequence Viewer  
  EDL06465 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000029196
  ENSMUSP00000029196.5
GenBank Protein Q8VHD6 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_569718   ⟸   NM_130451
- UniProtKB: Q8VHD6 (UniProtKB/Swiss-Prot),   A2A4V1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000029196   ⟸   ENSMUST00000029196
Protein Domains
Major facilitator superfamily (MFS) profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8VHD6-F1-model_v2 AlphaFold Q8VHD6 1-536 view protein structure

Promoters
RGD ID:6832749
Promoter ID:MM_KWN:33012
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day3,   Lung,   MEF_B4,   MEF_B6
Transcripts:OTTMUST00000002184
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv362165,329,054 - 165,329,554 (+)MPROMDB
RGD ID:6879736
Promoter ID:EPDNEW_M3319
Type:single initiation site
Name:Slc2a10_1
Description:Mus musculus solute carrier family 2 , member 10 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm382165,503,903 - 165,503,963EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2156687 AgrOrtholog
Ensembl Genes ENSMUSG00000027661 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000029196 ENTREZGENE
  ENSMUST00000029196.5 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.1250.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro MFS_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MFS_sugar_transport-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MFS_Sugar_Transporter UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MFS_trans_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sugar/inositol_transpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sugar_transporter_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:170441 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:2156687 ENTREZGENE
NCBI Gene 170441 ENTREZGENE
PANTHER D-XYLOSE-PROTON SYMPORTER-LIKE 2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Sugar_tr UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Slc2a10 PhenoGen
PRINTS SUGRTRNSPORT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE MFS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SUGAR_TRANSPORT_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF103473 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A2A4V1 ENTREZGENE, UniProtKB/TrEMBL
  GTR10_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE