Lrrc49 (leucine rich repeat containing 49) - Rat Genome Database

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Gene: Lrrc49 (leucine rich repeat containing 49) Ictidomys tridecemlineatus
Analyze
Symbol: Lrrc49
Name: leucine rich repeat containing 49
RGD ID: 12512847
Description: ASSOCIATED WITH Bloom syndrome (ortholog); colorectal cancer (ortholog); FOUND IN centriolar satellite (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: leucine rich repeat containing 49, transcript variant X1; leucine rich repeat containing 49, transcript variant X2; leucine rich repeat containing 49, transcript variant X3; leucine-rich repeat-containing protein 49
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640112,568,323 - 112,729,798 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647130,416,174 - 30,577,874 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647130,416,179 - 30,578,312 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Lrrc49
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640112,568,323 - 112,729,798 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647130,416,174 - 30,577,874 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647130,416,179 - 30,578,312 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LRRC49
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381570,853,378 - 71,053,658 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1570,853,239 - 71,053,658 (+)EnsemblGRCh38hg38GRCh38
GRCh371571,145,717 - 71,345,997 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361568,972,041 - 69,129,490 (+)NCBINCBI36Build 36hg18NCBI36
Celera1548,075,878 - 48,233,321 (+)NCBICelera
Cytogenetic Map15q23NCBI
HuRef1548,020,472 - 48,177,963 (+)NCBIHuRef
CHM1_11571,303,192 - 71,460,675 (+)NCBICHM1_1
T2T-CHM13v2.01568,676,342 - 68,876,951 (+)NCBIT2T-CHM13v2.0
Lrrc49
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39960,494,507 - 60,595,460 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl960,476,142 - 60,595,441 (-)EnsemblGRCm39 Ensembl
GRCm38960,587,224 - 60,688,167 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl960,568,859 - 60,688,158 (-)EnsemblGRCm38mm10GRCm38
MGSCv37960,435,036 - 60,535,941 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36960,385,246 - 60,485,917 (-)NCBIMGSCv36mm8
Celera957,812,803 - 57,913,421 (-)NCBICelera
Cytogenetic Map9BNCBI
cM Map932.75NCBI
Lrrc49
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8869,948,962 - 70,056,579 (-)NCBIGRCr8
mRatBN7.2861,053,264 - 61,160,695 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl861,053,267 - 61,160,850 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx866,561,249 - 66,668,708 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0864,834,189 - 64,941,267 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0862,703,669 - 62,811,138 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0865,481,584 - 65,587,687 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl865,481,592 - 65,587,658 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0865,233,813 - 65,339,662 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4864,524,550 - 64,631,904 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1864,543,611 - 64,650,971 (-)NCBI
Celera860,480,044 - 60,587,218 (-)NCBICelera
Cytogenetic Map8q24NCBI
Lrrc49
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554505,903,266 - 6,030,279 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554505,903,345 - 6,030,279 (-)NCBIChiLan1.0ChiLan1.0
LRRC49
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21660,155,994 - 60,316,144 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11564,319,908 - 64,479,628 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01549,841,934 - 50,023,736 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11568,608,412 - 68,769,334 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1568,589,175 - 68,769,334 (+)Ensemblpanpan1.1panPan2
LRRC49
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13034,580,906 - 34,737,181 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3034,581,241 - 34,737,009 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3034,515,159 - 34,673,673 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03034,781,934 - 34,938,531 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3034,782,217 - 34,938,848 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13034,728,801 - 34,893,909 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03034,766,753 - 34,921,966 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03035,018,625 - 35,177,587 (+)NCBIUU_Cfam_GSD_1.0
LRRC49
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1168,544,421 - 168,700,891 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11168,553,361 - 168,711,739 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21186,834,369 - 186,981,844 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LRRC49
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12612,405,249 - 12,568,597 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2612,405,721 - 12,567,987 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666048128,921,019 - 129,151,558 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Lrrc49
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247812,848,502 - 2,990,738 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247812,848,567 - 3,007,102 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSSTOT00000000947   ⟹   ENSSTOP00000000848
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_00493647130,416,610 - 30,577,732 (+)Ensembl
Ensembl Acc Id: ENSSTOT00000033215   ⟹   ENSSTOP00000025834
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_00493647130,416,174 - 30,577,874 (+)Ensembl
RefSeq Acc Id: XM_005316743   ⟹   XP_005316800
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024408640112,568,398 - 112,729,798 (+)NCBI
SpeTri2.0NW_00493647130,416,532 - 30,578,312 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005316744   ⟹   XP_005316801
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024408640112,568,323 - 112,729,798 (+)NCBI
SpeTri2.0NW_00493647130,416,179 - 30,577,874 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021727958   ⟹   XP_021583633
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024408640112,577,385 - 112,729,798 (+)NCBI
SpeTri2.0NW_00493647130,425,530 - 30,578,311 (+)NCBI
Sequence:
RefSeq Acc Id: XM_040274134   ⟹   XP_040130068
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024408640112,625,545 - 112,729,798 (+)NCBI
RefSeq Acc Id: XP_005316801   ⟸   XM_005316744
- Peptide Label: isoform X2
- UniProtKB: A0A287CX49 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005316800   ⟸   XM_005316743
- Peptide Label: isoform X1
- UniProtKB: I3LXN0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021583633   ⟸   XM_021727958
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_040130068   ⟸   XM_040274134
- Peptide Label: isoform X4
Ensembl Acc Id: ENSSTOP00000000848   ⟸   ENSSTOT00000000947
Ensembl Acc Id: ENSSTOP00000025834   ⟸   ENSSTOT00000033215


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000000941 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000000947.3 UniProtKB/TrEMBL
  ENSSTOT00000033215.1 UniProtKB/TrEMBL
Gene3D-CATH 3.80.10.10 UniProtKB/TrEMBL
InterPro Cilia_flagella_integrity UniProtKB/TrEMBL
  Leu-rich_rpt UniProtKB/TrEMBL
  Leu-rich_rpt_4 UniProtKB/TrEMBL
  Leu-rich_rpt_typical-subtyp UniProtKB/TrEMBL
  LRR_dom_sf UniProtKB/TrEMBL
NCBI Gene Lrrc49 ENTREZGENE
PANTHER CENTROSOMAL PROTEIN 97KDA, ISOFORM B-RELATED UniProtKB/TrEMBL
  PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT SDS22-RELATED UniProtKB/TrEMBL
Pfam LRR_4 UniProtKB/TrEMBL
  LRR_9 UniProtKB/TrEMBL
PROSITE LRR UniProtKB/TrEMBL
SMART LRR_SD22 UniProtKB/TrEMBL
  LRR_TYP UniProtKB/TrEMBL
Superfamily-SCOP L domain-like UniProtKB/TrEMBL
UniProt A0A287CX49 ENTREZGENE, UniProtKB/TrEMBL
  I3LXN0 ENTREZGENE, UniProtKB/TrEMBL