RPRD1B (regulation of nuclear pre-mRNA domain containing 1B) - Rat Genome Database

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Gene: RPRD1B (regulation of nuclear pre-mRNA domain containing 1B) Canis lupus familiaris
Analyze
Symbol: RPRD1B
Name: regulation of nuclear pre-mRNA domain containing 1B
RGD ID: 12098589
Description: ENCODES a protein that exhibits identical protein binding (inferred); RNA polymerase II C-terminal domain binding (inferred); RNA polymerase II complex binding (inferred); INVOLVED IN mRNA 3'-end processing (inferred); positive regulation of cell population proliferation (inferred); positive regulation of transcription by RNA polymerase II (inferred); ASSOCIATED WITH colon adenocarcinoma (ortholog); esophageal cancer (ortholog); ovarian serous cystadenocarcinoma (ortholog); FOUND IN nucleoplasm (inferred); nucleus (inferred); transcription preinitiation complex (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: regulation of nuclear pre-mRNA domain-containing protein 1B
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12426,552,487 - 26,604,586 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2426,552,859 - 26,602,129 (+)EnsemblCanFam3.1 EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2426,198,032 - 26,250,191 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02427,248,879 - 27,301,053 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2427,248,916 - 27,301,049 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12426,523,441 - 26,575,560 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02426,630,968 - 26,683,267 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02427,118,995 - 27,171,089 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
RPRD1B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12426,552,487 - 26,604,586 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2426,552,859 - 26,602,129 (+)EnsemblCanFam3.1 EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2426,198,032 - 26,250,191 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02427,248,879 - 27,301,053 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2427,248,916 - 27,301,049 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12426,523,441 - 26,575,560 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02426,630,968 - 26,683,267 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02427,118,995 - 27,171,089 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
RPRD1B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382038,033,746 - 38,092,364 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2038,033,514 - 38,127,780 (+)EnsemblGRCh38.p14 Ensemblhg38GRCh38
GRCh372036,662,148 - 36,720,766 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362036,095,362 - 36,154,180 (+)NCBIBuild 36Build 36hg18NCBI36
Build 342036,095,466 - 36,154,627NCBI
Celera2033,369,018 - 33,427,835 (+)NCBICelera
Cytogenetic Map20q11.23NCBI
HuRef2033,397,715 - 33,456,630 (+)NCBIHuRef
CHM1_12036,564,987 - 36,624,087 (+)NCBICHM1_1
T2T-CHM13v2.02039,758,090 - 39,816,692 (+)NCBIT2T-CHM13v2.0
Rprd1b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392157,870,395 - 157,920,127 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2157,870,344 - 157,974,217 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm382158,028,475 - 158,078,207 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2158,028,497 - 158,132,297 (+)EnsemblGRCm38.p6 Ensemblmm10GRCm38
MGSCv372157,854,530 - 157,903,056 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv362157,720,235 - 157,768,761 (+)NCBIMGSCv36mm8
Celera2163,971,143 - 164,021,857 (+)NCBICelera
Cytogenetic Map2H1NCBI
cM Map278.72NCBI
Rprd1b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83167,102,909 - 167,149,184 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl3167,102,859 - 167,206,374 (+)EnsemblGRCr8
mRatBN7.23146,682,975 - 146,729,251 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3146,682,922 - 146,786,452 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx3150,508,298 - 150,554,579 (+)NCBIUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03159,008,048 - 159,054,327 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03156,749,375 - 156,795,678 (+)NCBIUTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd3165,200,550 - 165,246,851 (+)NCBI
Lyon_Normotensive3172,053,818 - 172,100,096 (+)NCBI
Lyon_Hypertensive3164,028,731 - 164,075,032 (+)NCBI
F344_StmMcwi3144,921,802 - 144,968,099 (+)NCBI
Rnor_6.03154,507,029 - 154,553,312 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3154,507,035 - 154,553,312 (+)EnsemblRnor_6.0 Ensemblrn6Rnor6.0
Rnor_5.03161,050,861 - 161,097,241 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.43148,736,594 - 148,783,743 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera3145,384,095 - 145,430,271 (+)NCBICelera
RGSC_v3.13148,642,866 - 148,687,424 (+)NCBI
Cytogenetic Map3q42NCBI
Rprd1b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544518,561,799 - 18,676,243 (-)EnsemblChiLan1.0 Ensembl
ChiLan1.0NW_00495544518,622,018 - 18,676,243 (-)NCBIChiLan1.0ChiLan1.0
RPRD1B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22143,760,219 - 43,833,085 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12043,753,317 - 43,826,183 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02034,354,626 - 34,426,333 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12035,467,980 - 35,532,113 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2035,467,980 - 35,532,113 (+)EnsemblPanPan1.1 EnsemblpanPan2panpan1.1
Rprd1b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mIctTri1.hap15180,815,183 - 180,865,582 (+)NCBImIctTri1.hap1
HiC_Itri_2NW_024408640175,446,356 - 175,503,787 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365613,245,687 - 3,303,185 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365613,245,697 - 3,303,181 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RPRD1B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1741,094,032 - 41,176,855 (+)EnsemblSscrofa11.1 EnsemblsusScr11Sscrofa11.1
Sscrofa11.11741,093,970 - 41,172,617 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21746,508,130 - 46,564,341 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RPRD1B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mChlSab1.0.hap1226,027,657 - 26,085,424 (-)NCBImChlSab1.0.hap1
Vero_WHO_p1.0NW_02366605074,507,065 - 74,564,694 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
ChlSab1.1225,659,232 - 25,717,022 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl225,659,236 - 25,716,879 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Rprd1b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248421,571,112 - 1,629,800 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
HetGla_female_1.0 EnsemblNW_0046248421,509,117 - 1,630,193 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
Naked mole-rat maternal Ensembl1571,680,382 - 71,800,612 (-)Ensembl
Rprd1b
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v15137,371,811 - 137,417,662 (+)NCBIRrattus_CSIRO_v1Rrattus_CSIRO_v1

Variants

.
Variants in RPRD1B
368 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence


Ensembl Acc Id: ENSCAFT00000014042   ⟹   ENSCAFP00000012989
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2426,552,859 - 26,602,129 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845050871   ⟹   ENSCAFP00845039880
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2427,248,916 - 27,301,049 (+)Ensembl
RefSeq Acc Id: XM_022409434   ⟹   XP_022265142
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12426,552,487 - 26,597,058 (+)NCBI
Dog10K_Boxer_Tasha2426,198,032 - 26,242,780 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038433806   ⟹   XP_038289734
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02427,248,884 - 27,301,053 (+)NCBI
RefSeq Acc Id: XM_038433807   ⟹   XP_038289735
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02427,248,879 - 27,293,642 (+)NCBI
RefSeq Acc Id: XM_038508957   ⟹   XP_038364885
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12426,523,446 - 26,575,560 (+)NCBI
RefSeq Acc Id: XM_038508958   ⟹   XP_038364886
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12426,523,441 - 26,568,151 (+)NCBI
RefSeq Acc Id: XM_038572289   ⟹   XP_038428217
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02427,119,000 - 27,171,089 (+)NCBI
RefSeq Acc Id: XM_038572290   ⟹   XP_038428218
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02427,118,995 - 27,163,678 (+)NCBI
RefSeq Acc Id: XM_038636542   ⟹   XP_038492470
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02426,630,972 - 26,683,267 (+)NCBI
RefSeq Acc Id: XM_038636543   ⟹   XP_038492471
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02426,630,968 - 26,675,861 (+)NCBI
RefSeq Acc Id: XM_542990   ⟹   XP_542990
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12426,552,491 - 26,604,586 (+)NCBI
Dog10K_Boxer_Tasha2426,198,037 - 26,250,191 (+)NCBI
Sequence:
RefSeq Acc Id: XP_542990   ⟸   XM_542990
- Peptide Label: isoform X1
- UniProtKB: A0A8C0KHJ7 (UniProtKB/TrEMBL),   A0A8I3SBP4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_022265142   ⟸   XM_022409434
- Peptide Label: isoform X2
- Sequence:
Ensembl Acc Id: ENSCAFP00000012989   ⟸   ENSCAFT00000014042
RefSeq Acc Id: XP_038364886   ⟸   XM_038508958
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038364885   ⟸   XM_038508957
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038492471   ⟸   XM_038636543
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038492470   ⟸   XM_038636542
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038289735   ⟸   XM_038433807
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038289734   ⟸   XM_038433806
- Peptide Label: isoform X1
- UniProtKB: A0A8C0KHJ7 (UniProtKB/TrEMBL),   A0A8I3SBP4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038428218   ⟸   XM_038572290
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038428217   ⟸   XM_038572289
- Peptide Label: isoform X1
- UniProtKB: A0A8C0KHJ7 (UniProtKB/TrEMBL),   A0A8I3SBP4 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845039880   ⟸   ENSCAFT00845050871
Protein Domains
CID


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000008832 Ensembl
  ENSCAFG00845028792 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00845050871 ENTREZGENE
  ENSCAFT00845050871.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.90 UniProtKB/TrEMBL
  6.10.250.2560 UniProtKB/TrEMBL
InterPro CID_dom UniProtKB/TrEMBL
  CREPT UniProtKB/TrEMBL
  ENTH_VHS UniProtKB/TrEMBL
  RPRD1B_CID UniProtKB/TrEMBL
NCBI Gene RPRD1B ENTREZGENE
PANTHER CYCLIN-DEPENDENT KINASE INHIBITOR-RELATED PROTEIN UniProtKB/TrEMBL
  REGULATION OF NUCLEAR PRE-MRNA DOMAIN-CONTAINING PROTEIN 1B UniProtKB/TrEMBL
Pfam CID UniProtKB/TrEMBL
  CREPT UniProtKB/TrEMBL
PROSITE CID UniProtKB/TrEMBL
SMART RPR UniProtKB/TrEMBL
Superfamily-SCOP SSF48464 UniProtKB/TrEMBL
UniProt A0A8C0KHJ7 ENTREZGENE
  A0A8I3SBP4 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:45727 ENTREZGENE