YY2 (YY2 transcription factor) - Rat Genome Database

Name: YY2
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: YY2 (YY2 transcription factor) Pan paniscus

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Symbol:

YY2

Name:

YY2 transcription factor

RGD ID:

11683650

Description:

ENCODES a protein that exhibits cis-regulatory region sequence-specific DNA binding (inferred); DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); INVOLVED IN positive regulation of transcription by RNA polymerase II (inferred); regulation of transcription by RNA polymerase II (inferred); ASSOCIATED WITH autistic disorder (ortholog); ichthyosis follicularis-alopecia-photophobia syndrome 1 (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN chromatin (inferred); nucleus (inferred); PcG protein complex (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

transcription factor YY2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	YY2 (YY2 transcription factor)	NCBI	Ortholog
Mus musculus (house mouse):	Yy2 (Yy2 transcription factor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Yy2 (YY2 transcription factor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	YY2 (YY2 transcription factor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Yy2 (YY2 transcription factor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	YY2 (YY2 transcription factor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Yy2 (YY2 transcription factor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	X	23,662,228 - 23,677,032 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	X	23,665,506 - 23,680,423 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	X	14,486,444 - 14,489,457 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	X	21,842,676 - 21,844,949 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	X	21,842,693 - 21,843,812 (+)	Ensembl	panpan1.1		panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autistic disorder (ISO)

ichthyosis follicularis-alopecia-photophobia syndrome 1 (ISO)

Neurodevelopmental Disorders (ISO)

osteogenesis imperfecta type 19 (ISO)

syndromic X-linked intellectual disability Lubs type (ISO)

X-linked keratosis follicularis spinulosa decalvans (ISO)

X-linked mutilating palmoplantar keratoderma with periorificial keratotic plaques (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

positive regulation of transcription by RNA polymerase II (IEA)

regulation of transcription by RNA polymerase II (IEA)

Cellular Component

chromatin (IEA)

nucleus (IEA)

PcG protein complex (IEA)

transcription regulator complex (IEA)

Molecular Function

cis-regulatory region sequence-specific DNA binding (IEA)

DNA-binding transcription activator activity, RNA polymerase II-specific (IEA)

DNA-binding transcription factor activity, RNA polymerase II-specific (IEA)

RNA polymerase II cis-regulatory region sequence-specific DNA binding (IEA)

sequence-specific DNA binding (IEA)

sequence-specific double-stranded DNA binding (IEA)

References

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

YY2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	X	23,662,228 - 23,677,032 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	X	23,665,506 - 23,680,423 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	X	14,486,444 - 14,489,457 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	X	21,842,676 - 21,844,949 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	X	21,842,693 - 21,843,812 (+)	Ensembl	panpan1.1		panPan2

YY2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	X	21,855,987 - 21,858,740 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	X	21,855,987 - 21,858,740 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	X	21,874,105 - 21,876,858 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	X	21,784,524 - 21,785,642 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	X	21,634,259 - 21,635,378	NCBI
Celera	X	25,995,801 - 25,998,522 (+)	NCBI		Celera
Cytogenetic Map	X	p22.12	NCBI
HuRef	X	19,615,092 - 19,617,813 (+)	NCBI		HuRef
CHM1_1	X	21,904,524 - 21,907,264 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	X	21,439,288 - 21,442,041 (+)	NCBI		T2T-CHM13v2.0

Yy2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	X	156,349,115 - 156,351,981 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	X	156,349,115 - 156,351,981 (-)	Ensembl		GRCm39 Ensembl
GRCm38	X	157,566,119 - 157,568,985 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	X	157,566,119 - 157,568,985 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	X	154,004,051 - 154,006,917 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
Celera	X	140,818,791 - 140,821,630 (-)	NCBI		Celera
Cytogenetic Map	X	F4	NCBI
cM Map	X	72.57	NCBI

Yy2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	41,253,481 - 41,257,103 (+)	NCBI		GRCr8
mRatBN7.2	X	37,438,425 - 37,442,047 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	37,410,811 - 37,464,430 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	X	38,637,085 - 38,640,706 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	42,104,280 - 42,107,901 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	39,788,991 - 39,792,612 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	40,285,923 - 40,289,545 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
RGSC_v3.4	X	58,737,493 - 58,738,623 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	X	38,066,476 - 38,070,098 (+)	NCBI		Celera
Cytogenetic Map	X	q21	NCBI

YY2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	X	17,672,528 - 17,676,552 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
ROS_Cfam_1.0	X	17,632,553 - 17,636,290 (+)	NCBI		ROS_Cfam_1.0
UMICH_Zoey_3.1	X	17,666,733 - 17,669,609 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	X	17,688,471 - 17,692,205 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	X	17,748,713 - 17,752,450 (+)	NCBI		UU_Cfam_GSD_1.0

Yy2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	X	10,667,817 - 10,670,212 (+)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936624	2,487,983 - 2,489,630 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

YY2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	X	20,337,022 - 20,338,701 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666056	22,189,608 - 22,192,528 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Yy2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624829	6,811,644 - 6,815,253 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_003845969	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_055106222	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000024	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSPPAT00000042453 ⟹ ENSPPAP00000019683

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	X	21,842,693 - 21,843,812 (+)	Ensembl

RefSeq Acc Id:

XM_055106222 ⟹ XP_054962197

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	X	23,662,228 - 23,677,032 (+)	NCBI
NHGRI_mPanPan1	X	23,665,506 - 23,680,423 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_054962197	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000019683.1

Ensembl Acc Id:

ENSPPAP00000019683 ⟸ ENSPPAT00000042453

RefSeq Acc Id:	XP_054962197 ⟸ XM_055106222
- UniProtKB:	A0A2R9AR94 (UniProtKB/TrEMBL)

Protein Domains

C2H2-type

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000033052	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000042453.1	UniProtKB/TrEMBL
Gene3D-CATH	Classic Zinc Finger	UniProtKB/TrEMBL
InterPro	YY1-like	UniProtKB/TrEMBL
	Znf_C2H2_sf	UniProtKB/TrEMBL
	Znf_C2H2_type	UniProtKB/TrEMBL
NCBI Gene	YY2	ENTREZGENE
PANTHER	TRANSCRIPTION FACTOR YY2	UniProtKB/TrEMBL
	TRANSCRIPTIONAL REPRESSOR PROTEIN YY	UniProtKB/TrEMBL
Pfam	zf-C2H2	UniProtKB/TrEMBL
PIRSF	TF_Yin_yang	UniProtKB/TrEMBL
PROSITE	ZINC_FINGER_C2H2_1	UniProtKB/TrEMBL
	ZINC_FINGER_C2H2_2	UniProtKB/TrEMBL
SMART	ZnF_C2H2	UniProtKB/TrEMBL
Superfamily-SCOP	SSF57667	UniProtKB/TrEMBL
UniProt	A0A2R9AR94	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

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MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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