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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1603623
Species: Homo sapiens
RGD Object: Gene
Symbol: SMURF1
Name: SMAD specific E3 ubiquitin protein ligase 1
Acc ID: CHEBI:61057
Term: tacrolimus hydrate
Definition: A hydrate that is the monohydrate form of tacrolimus.
Chemical ID: MESH:D016559
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
SMURF1multiple interactionsEXP 6480464CTDTacrolimus inhibits the reaction [FKBP1A protein promotes the reaction [SMURF1 protein binds to SMAD7 protein binds to ACVR1B protein]]; Tacrolimus inhibits the reaction [SMAD7 protein binds to SMURF1 protein]PMID:16720724
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