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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 737513
Species: Homo sapiens
RGD Object: Gene
Symbol: OPRM1
Name: opioid receptor mu 1
Acc ID: CHEBI:180536
Term: 7-Hydroxymitragynine
Definition: null
Chemical ID: MESH:C482678
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
OPRM1increases activityEXP 6480464CTD7-hydroxymitragynine results in increased activity of OPRM1 proteinPMID:32734307
OPRM1multiple interactionsEXP 6480464CTD7-hydroxymitragynine affects the reaction [Enkephalin, Ala(2)-MePhe(4)-Gly(5)- binds to and results in increased activity of OPRM1 protein]; 7-hydroxymitragynine binds to and results in increased activity of OPRM1 proteinPMID:27192616
OPRM1affects bindingISOOprm1 (Mus musculus)6480464CTD7-hydroxymitragynine binds to OPRM1 proteinPMID:27192616
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