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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735934
Species: Homo sapiens
RGD Object: Gene
Symbol: C5
Name: complement C5
Acc ID: CHEBI:15647
Term: leukotriene B4
Definition: A leukotriene composed of (6Z,8E,10E,14Z)-icosatetraenoic acid having (5S)- and (12R)-hydroxy substituents. It is a lipid mediator of inflammation that is generated from arachidonic acid via the 5-lipoxygenase pathway.
Chemical ID: MESH:D007975
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
C5increases abundanceEXP 6480464CTDC5 protein results in increased abundance of Leukotriene B4PMID:10477617
C5multiple interactionsEXP 6480464CTDMK 0591 inhibits the reaction [C5 protein results in increased abundance of Leukotriene B4]PMID:10477617
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