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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735355
Species: Homo sapiens
RGD Object: Gene
Symbol: GABRB2
Name: gamma-aminobutyric acid type A receptor subunit beta2
Acc ID: CHEBI:34531
Term: Alphaxolone
Definition: A corticosteroid hormone that has formula C21H32O3.
Chemical ID: MESH:C006477
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
GABRB2affects response to substanceISOGabrb2 (Rattus norvegicus)6480464CTDGABRB2 protein affects the susceptibility to alphaxalonePMID:12939268
GABRB2multiple interactionsISOGabrb2 (Rattus norvegicus)6480464CTDalphaxalone promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; alphaxalone promotes the reaction [Muscimol binds to GABRB2 protein]; alphaxalone results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]PMID:12939268 PMID:8397295
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