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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735284
Species: Mus musculus
RGD Object: Gene
Symbol: Elavl1
Name: ELAV like RNA binding protein 1
Acc ID: CHEBI:94552
Term: sepantronium
Definition: An organic cation that is 1-(2-methoxyethyl)-2-methyl-1H-naphtho[2,3-d]imidazole-4,9-dione in which the nitrogen at position 3 of the napthoimidazole moiety has been alkylated by a pyrazin-2-ylmethyl group.
Chemical ID: MESH:C523798
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Elavl1decreases expressionISOELAVL1 (Homo sapiens)6480464CTDsepantronium results in decreased expression of ELAVL1 proteinPMID:31837377
Elavl1multiple interactionsISOELAVL1 (Homo sapiens)6480464CTD3-methyladenine inhibits the reaction [sepantronium results in decreased expression of and results in decreased stability of ELAVL1 mRNA]; 3-methyladenine inhibits the reaction [sepantronium results in decreased expression of ELAVL1 protein]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [sepantronium results in decreased expression of and results in decreased stability of ELAVL1 mRNA]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [sepantronium results in decreased expression of ELAVL1 protein]; ELAVL1 protein inhibits the reaction [sepantronium results in decreased expression of BIRC5 mRNA]; ELAVL1 protein inhibits the reaction [sepantronium results in decreased expression of BIRC5 protein]; ELAVL1 protein inhibits the reaction [sepantronium results in decreased expression of MCL1 mRNA]; ELAVL1 protein inhibits the reaction [sepantronium results in decreased expression of MCL1 protein]; sepantronium results in decreased expression of and results in decreased stability of ELAVL1 mRNAPMID:31837377
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