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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 734274
Species: Homo sapiens
RGD Object: Gene
Symbol: NTRK1
Name: neurotrophic receptor tyrosine kinase 1
Acc ID: CHEBI:30621
Term: diarsenic trioxide
Definition: An arsenic oxide in which arsenic and oxygen atoms are present in the ratio 2:3.
Chemical ID: MESH:C006632
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
NTRK1decreases expressionEXP 6480464CTDArsenic Trioxide results in decreased expression of NTRK1PMID:16569477
NTRK1increases expressionEXP 6480464CTDArsenic Trioxide results in increased expression of NTRK1 mRNA; Arsenic Trioxide results in increased expression of NTRK1 proteinPMID:29898774
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