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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733522
Species: Mus musculus
RGD Object: Gene
Symbol: Sdha
Name: succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
Acc ID: CHEBI:131461
Term: 3-bromopyruvic acid
Definition: A 2-oxo monocarboxylic acid that is pyruvic acid in which one of the methyl hydrogens is replaced by bromine. Synthetic brominated derivative and structural analog of pyruvic acid. Highly reactive alkylating agent. Anti-cancer drug
Chemical ID: MESH:C017092
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sdhadecreases expressionEXP 6480464CTDbromopyruvate results in decreased expression of SDHA mRNAPMID:28433571
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