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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733316
Species: Homo sapiens
RGD Object: Gene
Symbol: KCNJ4
Name: potassium inwardly rectifying channel subfamily J member 4
Acc ID: CHEBI:3441
Term: carvedilol
Definition: A member of the class of carbazoles that is an adrenergic antagonist with non-selective beta- and alpha-1 receptor blocking properties which helps in the management of congestive heart failure.
Chemical ID: MESH:C043211
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
KCNJ4multiple interactionsEXP 6480464CTDCarvedilol binds to and results in decreased activity of KCNJ4 protein; Phosphatidylinositol Phosphates inhibits the reaction [Carvedilol binds to and results in decreased activity of KCNJ4 protein]PMID:21663737
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