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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732758
Species: Mus musculus
RGD Object: Gene
Symbol: Ptk2
Name: PTK2 protein tyrosine kinase 2
Acc ID: CHEBI:28939
Term: N-acetyl-L-cysteine
Definition: An N-acetyl-L-amino acid that is the N-acetylated derivative of the natural amino acid L-cysteine.
Chemical ID: MESH:D000111
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ptk2multiple interactionsISOPTK2 (Homo sapiens)6480464CTDAcetylcysteine inhibits the reaction [[[Thimerosal results in increased abundance of Reactive Oxygen Species] which results in increased activity of CASP3 protein] which results in increased cleavage of PTK2 protein]PMID:17888894
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