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GENE - TERM ANNOTATION REPORT

RGD ID: 732176
Species: Homo sapiens
RGD Object: Gene
Symbol: CXCR4
Name: C-X-C motif chemokine receptor 4
Acc ID: GO:0016493
Term: C-C chemokine receptor activity
Definition: Combining with a C-C chemokine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. C-C chemokines do not have an amino acid between the first two cysteines of the characteristic four-cysteine motif.
Definition Source(s): GOC:signaling, PMID:8662823
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CXCR4enablesIBAMGI:103011 or MGI:104616 or MGI:104618 or MGI:106185 or MGI:107182 or MGI:107824 or MGI:1096320 or MGI:1201402 or MGI:1333797 or MGI:1341902 or MGI:1891697 or PANTHER:PTN001628461 or UniProtKB:P32246 or UniProtKB:P32248 or UniProtKB:P51681 or UniProtKB:P51684150520179GO_Central GO_REF:0000033
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