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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731770
Species: Homo sapiens
RGD Object: Gene
Symbol: CCKAR
Name: cholecystokinin A receptor
Acc ID: CHEBI:4460
Term: devazepide
Definition: An indolecarboxamide obtained by formal condensation of the carboxy group of indole-2-carboxylic acid with the exocyclic amino group of (3S)-3-amino-1-methyl-5-phenyl-1,3-dihydro-1,4-benzodiazepin-2-one. A cholecystokinin antagonist used for treatment of gastrointestinal disorders.
Chemical ID: MESH:D020109
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CCKARmultiple interactionsEXP 6480464CTDDevazepide inhibits the reaction [CCKAR protein results in increased susceptibility to denatonium]PMID:18003792
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