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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731000
Species: Homo sapiens
RGD Object: Gene
Symbol: IL10RA
Name: interleukin 10 receptor subunit alpha
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
IL10RAincreases mutagenesisEXP 6480464CTDBenzo(a)pyrene results in increased mutagenesis of IL10RA genePMID:25435355
IL10RAdecreases expressionISOIl10ra (Mus musculus)6480464CTDBenzo(a)pyrene results in decreased expression of IL10RA mRNAPMID:21569818
IL10RAincreases expressionISOIl10ra (Mus musculus)6480464CTDBenzo(a)pyrene results in increased expression of IL10RA mRNAPMID:22228805
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