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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 708543
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Epha8
Name: Eph receptor A8
Acc ID: CHEBI:34696
Term: dieldrin
Definition: An organochlorine compound resulting from the epoxidation of the double bond of aldrin. It is the active metabolite of the proinsecticde aldrin.
Chemical ID: MESH:D004026
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Epha8affects methylationISOEpha8 (Mus musculus)6480464CTDDieldrin affects the methylation of EPHA8 genePMID:38995845
Epha8multiple interactionsISOEPHA8 (Homo sapiens)6480464CTD[Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in increased expression of EPHA8 mRNAPMID:28263720
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