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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 708530
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp4v3
Name: cytochrome P450, family 4, subfamily v, polypeptide 3
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp4v3decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of CYP4V2 mRNA; bisphenol A results in decreased expression of CYP4V3 mRNAPMID:25181051 PMID:34947998
Cyp4v3increases expressionEXP 6480464CTDbisphenol A results in increased expression of CYP4V3 mRNAPMID:33296240 PMID:35192832
Cyp4v3decreases expressionISOCyp4v3 (Mus musculus)6480464CTDbisphenol A results in decreased expression of CYP4V3 mRNAPMID:33221593
Cyp4v3increases expressionISOCYP4V2 (Homo sapiens)6480464CTDbisphenol A results in increased expression of CYP4V2 mRNAPMID:27685785 PMID:29275510 PMID:31715268
Cyp4v3increases expressionISOCyp4v3 (Mus musculus)6480464CTDbisphenol A results in increased expression of CYP4V3 mRNAPMID:38701888
Cyp4v3increases methylationISOCYP4V2 (Homo sapiens)6480464CTDbisphenol A results in increased methylation of CYP4V2 genePMID:31601247
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