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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69368
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Scn9a
Name: sodium voltage-gated channel alpha subunit 9
Acc ID: CHEBI:3387
Term: carbamazepine
Definition: A dibenzoazepine that is 5H-dibenzo[b,f]azepine carrying a carbamoyl substituent at the azepine nitrogen, used as an anticonvulsant.
Chemical ID: MESH:D002220
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Scn9aaffects activityISOSCN9A (Homo sapiens)6480464CTDCarbamazepine affects the activity of SCN9A protein mutant formPMID:19557861
Scn9aaffects response to substanceISOSCN9A (Homo sapiens)6480464CTDSCN9A gene mutant form affects the susceptibility to CarbamazepinePMID:17145499
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