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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69061
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pdk4
Name: pyruvate dehydrogenase kinase 4
Acc ID: CHEBI:81927
Term: enilconazole
Definition: A racemate comprising equimolar amounts of (R)- and (S)-enilconazole. A fungicide used to control a wide range of fungi including Tilletia and Helminthosporium spp. on fruit, vegetables and ornamentals. In veterinary medicine, it is used topically for the treatment of fungal skin infections in cattle, dogs, and horses; it is also used by inhalation for the treatment of aspergillosis in ostriches.
Chemical ID: MESH:C017435
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pdk4decreases expressionISOPDK4 (Homo sapiens)6480464CTDenilconazole results in decreased expression of PDK4 mRNAPMID:32201337
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