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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68353
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nr5a2
Name: nuclear receptor subfamily 5, group A, member 2
Acc ID: CHEBI:34372
Term: 4,4'-sulfonyldiphenol
Definition: A sulfone that is diphenyl sulfone in which both of the para hydrogens have been replaced by hydroxy groups.
Chemical ID: MESH:C543008
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nr5a2decreases expressionISONR5A2 (Homo sapiens)6480464CTDbisphenol S results in decreased expression of NR5A2 proteinPMID:33181973
Nr5a2multiple interactionsISONR5A2 (Homo sapiens)6480464CTD[bisphenol S co-treated with Fulvestrant] results in decreased methylation of NR5A2 genePMID:31601247
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