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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 628692
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Impa2
Name: inositol monophosphatase 2
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Impa2affects expressionEXP 6480464CTDTetrachlorodibenzodioxin affects the expression of IMPA2 mRNAPMID:34747641
Impa2increases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in increased expression of IMPA2 mRNA; Tetrachlorodibenzodioxin results in increased expression of IMPA2 proteinPMID:16054898 PMID:20959002 PMID:21215274 PMID:31511937 PMID:33387578
Impa2affects expressionISOIMPA2 (Homo sapiens)6480464CTDTetrachlorodibenzodioxin affects the expression of IMPA2 mRNAPMID:22298810
Impa2affects expressionISOImpa2 (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of IMPA2 mRNAPMID:21570461 PMID:26377647
Impa2decreases expressionISOIMPA2 (Homo sapiens)6480464CTDTetrachlorodibenzodioxin results in decreased expression of IMPA2 mRNAPMID:20106945 PMID:21632981
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