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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621738
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Khdrbs2
Name: KH RNA binding domain containing, signal transduction associated 2
Acc ID: CHEBI:28088
Term: genistein
Definition: A 7-hydroxyisoflavone with additional hydroxy groups at positions 5 and 4'. It is a phytoestrogenic isoflavone with antioxidant properties.
Chemical ID: MESH:D019833
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Khdrbs2multiple interactionsEXP 6480464CTD[Genistein co-treated with Diethylhexyl Phthalate] results in decreased expression of KHDRBS2 mRNAPMID:36674726
Khdrbs2decreases expressionISOKhdrbs2 (Mus musculus)6480464CTDGenistein results in decreased expression of KHDRBS2 mRNAPMID:32186404
Khdrbs2multiple interactionsISOKHDRBS2 (Homo sapiens)6480464CTDGenistein promotes the reaction [KHDRBS2 protein binds to ESR1 protein]PMID:27156127
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