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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621691
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pou2f3
Name: POU class 2 homeobox 3
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pou2f3decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of POU2F3 mRNAPMID:25181051
Pou2f3increases expressionEXP 6480464CTDbisphenol A results in increased expression of POU2F3 mRNAPMID:30816183 PMID:32528016
Pou2f3increases methylationEXP 6480464CTDbisphenol A results in increased methylation of POU2F3 genePMID:28505145
Pou2f3multiple interactionsEXP 6480464CTD[bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of POU2F3 mRNAPMID:36041667
Pou2f3affects methylationISOPou2f3 (Mus musculus)6480464CTDbisphenol A affects the methylation of POU2F3 promoterPMID:27334623
Pou2f3decreases expressionISOPOU2F3 (Homo sapiens)6480464CTDbisphenol A results in decreased expression of POU2F3 mRNAPMID:31715268 PMID:36828454
Pou2f3increases expressionISOPou2f3 (Mus musculus)6480464CTDbisphenol A results in increased expression of POU2F3 mRNAPMID:32156529
Pou2f3increases expressionISOPOU2F3 (Homo sapiens)6480464CTDbisphenol A results in increased expression of POU2F3 mRNAPMID:17989879
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