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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621667
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Grip1
Name: glutamate receptor interacting protein 1
Acc ID: CHEBI:39867
Term: valproic acid
Definition: A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Chemical ID: MESH:D014635
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Grip1affects expressionISOGRIP1 (Homo sapiens)6480464CTDValproic Acid affects the expression of GRIP1 mRNAPMID:25979313
Grip1affects expressionISOGrip1 (Mus musculus)6480464CTDValproic Acid affects the expression of GRIP1 mRNAPMID:17292431
Grip1decreases expressionISOGRIP1 (Homo sapiens)6480464CTDValproic Acid results in decreased expression of GRIP1 mRNAPMID:23179753 PMID:27188386
Grip1decreases palmitoylationISOGrip1 (Mus musculus)6480464CTDValproic Acid results in decreased palmitoylation of GRIP1 proteinPMID:26348896
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