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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621467
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Adam1a
Name: ADAM metallopeptidase domain 1a
Acc ID: CHEBI:7071
Term: N,N-diethyl-m-toluamide
Definition: A monocarboxylic acid amide resulting from the formal condensation of the carboxy group of m-toluic acid with the nitrogen of diethylamine. First developed by the U.S. Army in 1946 for use by military personnel in insect-infested areas, it is the most widely used insect repellent worldwide.
Chemical ID: MESH:D003671
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Adam1amultiple interactionsISOADAM1A (Homo sapiens)6480464CTD[fipronil co-treated with DEET] results in decreased expression of ADAM1A mRNAPMID:28991164
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