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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621256
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Lin7a
Name: lin-7 homolog A, crumbs cell polarity complex component
Acc ID: CHEBI:91108
Term: SB 431542
Definition: A member of the class of benzamides that is 4-(imidazol-2-yl)benzamide carrying additional 1,3-benzodioxol-5-yl and pyridin-2-yl substituents at positions 4 and 5 respectively on the imidazole ring.
Chemical ID: MESH:C459179
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Lin7aincreases expressionISOLIN7A (Homo sapiens)6480464CTD4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in increased expression of LIN7A proteinPMID:25670856
Lin7amultiple interactionsISOLIN7A (Homo sapiens)6480464CTD[NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of LIN7A mRNAPMID:27188386
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