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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621023
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Lama5
Name: laminin subunit alpha 5
Acc ID: CHEBI:34575
Term: bisphenol F
Definition: A bisphenol that is methane in which two of the hydrogens have been replaced by 4-hydroxyphenyl groups.
Chemical ID: MESH:C008745
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Lama5decreases expressionISOLama5 (Mus musculus)6480464CTDbisphenol F results in decreased expression of LAMA5 mRNAPMID:38685157
Lama5increases expressionISOLama5 (Mus musculus)6480464CTDbisphenol F results in increased expression of LAMA5 mRNAPMID:30951980
Lama5multiple interactionsISOLAMA5 (Homo sapiens)6480464CTD[bisphenol F co-treated with Fulvestrant] results in increased methylation of LAMA5 gene; [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of LAMA5 mRNAPMID:28628672 PMID:31601247
Lama5multiple interactionsISOLama5 (Mus musculus)6480464CTD[bisphenol F co-treated with Tretinoin] results in decreased expression of LAMA5 mRNAPMID:30951980
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