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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620995
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pde5a
Name: phosphodiesterase 5A
Acc ID: CHEBI:9464
Term: testosterone enanthate
Definition: An enanthate ester that has formula C26H40O3.
Chemical ID: MESH:C004648
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pde5aincreases expressionEXP 6480464CTDtestosterone enanthate results in increased expression of PDE5A mRNA; testosterone enanthate results in increased expression of PDE5A proteinPMID:20463352
Pde5amultiple interactionsEXP 6480464CTD[testosterone enanthate co-treated with Triptorelin Pamoate] results in increased expression of PDE5A mRNA; [testosterone enanthate co-treated with Triptorelin Pamoate] results in increased expression of PDE5A protein; Cyproterone Acetate inhibits the reaction [testosterone enanthate results in increased expression of PDE5A mRNA]PMID:20463352
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