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GENE - TERM ANNOTATION REPORT

RGD ID: 620845
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Apba2
Name: amyloid beta precursor protein binding family A member 2
Acc ID: GO:0007268
Term: chemical synaptic transmission
Definition: The vesicular release of classical neurotransmitter molecules from a presynapse, across a chemical synapse, the subsequent activation of neurotransmitter receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.
Definition Source(s): GOC:jl, MeSH:D009435
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Apba2acts_upstream_of_or_withinISOApba2 (Mus musculus)1624291RGDMGI:1860297 MGI:1888527 PMID:17167098

PMID:17167098
Apba2involved_inIBAMGI:1261791 or MGI:1860297 or MGI:1888527 or PANTHER:PTN000960968 or WB:WBGene000029991600115GO_CentralGO_REF:0000033

GO_REF:0000033
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