Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620591
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Rap2b
Name: RAP2B, member of RAS oncogene family
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Rap2bdecreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in decreased expression of RAP2B mRNAPMID:33387578
Rap2baffects expressionISORap2b (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of RAP2B mRNAPMID:21570461
Rap2bdecreases expressionISORap2b (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in decreased expression of RAP2B mRNAPMID:37854252
Rap2bincreases expressionISORAP2B (Homo sapiens)6480464CTDTetrachlorodibenzodioxin results in increased expression of RAP2B mRNAPMID:21632981
Rap2bincreases expressionISORap2b (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in increased expression of RAP2B mRNAPMID:19770486
Rap2bmultiple interactionsISORap2b (Mus musculus)6480464CTD[Tetrachlorodibenzodioxin co-treated with AHR gene mutant form] results in decreased expression of RAP2B mRNA; [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of RAP2B mRNAPMID:17942748 PMID:19465110
Go Back to source page   Continue to Ontology report