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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 61855
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gabra1
Name: gamma-aminobutyric acid type A receptor subunit alpha 1
Acc ID: CHEBI:8207
Term: (+)-pilocarpine
Definition: The (+)-enantiomer of pilocarpine.
Chemical ID: MESH:D010862
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gabra1decreases expressionEXP 6480464CTDPilocarpine results in decreased expression of GABRA1 mRNAPMID:20821261
Gabra1multiple interactionsEXP 6480464CTDbacoside A inhibits the reaction [Pilocarpine results in decreased expression of GABRA1 mRNA]; Carbamazepine inhibits the reaction [Pilocarpine results in decreased expression of GABRA1 mRNA]PMID:20821261
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