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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3865
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Timp3
Name: TIMP metallopeptidase inhibitor 3
Acc ID: CHEBI:17594
Term: hydroquinone
Definition: A benzenediol comprising benzene core carrying two hydroxy substituents para to each other.
Chemical ID: MESH:C031927
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Timp3decreases expressionEXP 6480464CTDhydroquinone results in decreased expression of TIMP3 mRNAPMID:33188856
Timp3multiple interactionsEXP 6480464CTD[[Cadmium Chloride results in increased abundance of Cadmium] which co-treated with hydroquinone] results in decreased expression of TIMP3 mRNA; Acetylcysteine inhibits the reaction [[[Cadmium Chloride results in increased abundance of Cadmium] which co-treated with hydroquinone] results in decreased expression of TIMP3 mRNA]; Acetylcysteine inhibits the reaction [hydroquinone results in decreased expression of TIMP3 mRNA]PMID:33188856
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