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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3787
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Abcc9
Name: ATP binding cassette subfamily C member 9
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Abcc9increases expressionEXP 6480464CTDEstradiol results in increased expression of ABCC9 mRNAPMID:32145629
Abcc9multiple interactionsEXP 6480464CTD[estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of ABCC9 mRNAPMID:32741896
Abcc9affects bindingISOAbcc9 (Mus musculus)6480464CTDEstradiol binds to ABCC9 protein mutant formPMID:19095654
Abcc9multiple interactionsISOAbcc9 (Mus musculus)6480464CTDEstradiol inhibits the reaction [Glyburide binds to ABCC9 protein mutant form]PMID:19095654
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