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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3761
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Sst
Name: somatostatin
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sstdecreases expressionEXP 6480464CTDbisphenol A results in decreased expression of SST mRNAPMID:25181051 PMID:34947998
Sstmultiple interactionsEXP 6480464CTDbisphenol A promotes the reaction [SST binds to SSTR2 protein alternative form]; Ro 15-4513 promotes the reaction [bisphenol A promotes the reaction [SST binds to SSTR2 protein alternative form]]; zolpidem promotes the reaction [bisphenol A promotes the reaction [SST binds to SSTR2 protein alternative form]]PMID:12060835
Sstdecreases expressionISOSst (Mus musculus)6480464CTDbisphenol A results in decreased expression of SST mRNAPMID:32156529 PMID:35598803
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