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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3442
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pth1r
Name: parathyroid hormone 1 receptor
Acc ID: CHEBI:35456
Term: cadmium dichloride
Definition: A cadmium coordination entity in which cadmium(2+) and Cl(-) ions are present in the ratio 2:1. Although considered to be ionic, it has considerable covalent character to its bonding.
Chemical ID: MESH:D019256
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pth1raffects expressionEXP 6480464CTDCadmium Chloride affects the expression of PTH1R mRNAPMID:22110744
Pth1rincreases expressionEXP 6480464CTDCadmium Chloride results in increased expression of PTH1R proteinPMID:23750309
Pth1rmultiple interactionsEXP 6480464CTDtelmisartan inhibits the reaction [Cadmium Chloride results in increased expression of PTH1R protein]PMID:23750309
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