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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3044
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Map2
Name: microtubule-associated protein 2
Acc ID: CHEBI:9288
Term: streptozocin
Definition: An N-nitrosourea that is an antibiotic produced by Streptomyces achromogenes. It is used as an antineoplastic agent and to induce diabetes in experimental animals.
Chemical ID: MESH:D013311
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Map2decreases expressionEXP 6480464CTDStreptozocin results in decreased expression of MAP2 proteinPMID:38049026
Map2multiple interactionsEXP 6480464CTDVitamin B 12 inhibits the reaction [Streptozocin results in decreased expression of MAP2 protein]PMID:38049026
Map2decreases expressionISOMap2 (Mus musculus)6480464CTDStreptozocin results in decreased expression of MAP2 proteinPMID:28499986
Map2multiple interactionsISOMap2 (Mus musculus)6480464CTDAcetylcysteine inhibits the reaction [Streptozocin results in decreased expression of MAP2 protein]; Physostigmine inhibits the reaction [Streptozocin results in decreased expression of MAP2 protein]PMID:28499986
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