GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ifng | increases expression | EXP | | 6480464 | CTD | Cyclophosphamide results in increased expression of IFNG protein | PMID:18848347 PMID:35906875 | Ifng | multiple interactions | EXP | | 6480464 | CTD | Quercetin inhibits the reaction [Cyclophosphamide results in increased expression of IFNG protein] | PMID:35906875 | Ifng | affects expression | ISO | Ifng (Mus musculus) | 6480464 | CTD | Cyclophosphamide affects the expression of IFNG mRNA | PMID:18957084 | Ifng | decreases expression | ISO | Ifng (Mus musculus) | 6480464 | CTD | Cyclophosphamide results in decreased expression of IFNG mRNA; Cyclophosphamide results in decreased expression of IFNG protein | PMID:11014644 PMID:21068404 PMID:32151603 PMID:37853057 | Ifng | decreases secretion | ISO | Ifng (Mus musculus) | 6480464 | CTD | Cyclophosphamide results in decreased secretion of IFNG protein | PMID:23395935 | Ifng | increases expression | ISO | Ifng (Mus musculus) | 6480464 | CTD | Cyclophosphamide results in increased expression of IFNG mRNA | PMID:11006010 PMID:15331540 PMID:22842586 | Ifng | multiple interactions | ISO | IFNG (Homo sapiens) | 6480464 | CTD | [Cyclophosphamide co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA | PMID:29594315 | Ifng | multiple interactions | ISO | Ifng (Mus musculus) | 6480464 | CTD | (4-formyl-9-methoxy-5-methyl-naphtho(2,3-b)furan-3-yl)methyl acetate inhibits the reaction [Cyclophosphamide results in decreased secretion of IFNG protein]; Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of IFNG mRNA]; ganoderic acid C2 inhibits the reaction [Cyclophosphamide results in decreased expression of IFNG protein]; IFNG protein inhibits the reaction [Cyclophosphamide results in increased abundance of Nitric Oxide]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased expression of IFNG mRNA]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased secretion of IFNG protein] | PMID:10607705 PMID:23395935 PMID:32151603 PMID:37853057 | | ||||||||||||||||||||||
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