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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2866
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ifng
Name: interferon gamma
Acc ID: CHEBI:34873
Term: N-nitrosodiethylamine
Definition: A nitrosamine that is N-ethylethanamine substituted by a nitroso group at the N-atom.
Chemical ID: MESH:D004052
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ifngmultiple interactionsEXP 6480464CTD2-Acetylaminofluorene inhibits the reaction [[Diethylnitrosamine co-treated with Methylnitrosourea co-treated with Butylhydroxybutylnitrosamine co-treated with diisopropanolnitrosamine co-treated with 1,2-Dimethylhydrazine] results in decreased expression of IFNG protein]; [Diethylnitrosamine co-treated with Methylnitrosourea co-treated with Butylhydroxybutylnitrosamine co-treated with diisopropanolnitrosamine co-treated with 1,2-Dimethylhydrazine] results in decreased expression of IFNG proteinPMID:14736494
Ifngaffects response to substanceISOIfng (Mus musculus)6480464CTDIFNG protein affects the susceptibility to DiethylnitrosaminePMID:15765122
Ifngincreases expressionISOIfng (Mus musculus)6480464CTDDiethylnitrosamine results in increased expression of IFNG mRNAPMID:15765122
Ifngmultiple interactionsISOIfng (Mus musculus)6480464CTDcapmatinib inhibits the reaction [Diethylnitrosamine results in increased expression of and results in increased secretion of IFNG protein]; Diethylnitrosamine results in increased expression of and results in increased secretion of IFNG proteinPMID:27553677
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