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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2866
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ifng
Name: interferon gamma
Acc ID: CHEBI:29073
Term: L-ascorbic acid
Definition: The L-enantiomer of ascorbic acid and conjugate acid of L-ascorbate.
Chemical ID: MESH:D001205
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ifngmultiple interactionsEXP 6480464CTDAscorbic Acid inhibits the reaction [Formaldehyde results in increased expression of IFNG mRNA]PMID:27020608
Ifngdecreases expressionISOIfng (Mus musculus)6480464CTDAscorbic Acid results in decreased expression of IFNG proteinPMID:14624943
Ifngmultiple interactionsISOIfng (Mus musculus)6480464CTDIFNG protein promotes the reaction [Ascorbic Acid promotes the reaction [Quartz results in increased secretion of TNF protein]]PMID:19298665
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