GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ifng | multiple interactions | EXP | | 6480464 | CTD | Resveratrol inhibits the reaction [[IL1B protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; Resveratrol inhibits the reaction [[IL1B protein co-treated with IFNG protein] results in increased expression of NOS2 protein]; Resveratrol inhibits the reaction [[IL1B protein co-treated with IFNG protein] results in increased phosphorylation of AKT1 protein]; Resveratrol inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein co-treated with TNF protein] results in increased abundance of Nitric Oxide]; Resveratrol inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein co-treated with TNF protein] results in increased abundance of Reactive Oxygen Species]; Resveratrol inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein co-treated with TNF protein] results in increased expression of NOS2 mRNA]; Resveratrol inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein co-treated with TNF protein] results in increased expression of NOS2 protein]; Resveratrol inhibits the reaction [sulfoxaflor results in increased expression of IFNG protein]; Resveratrol promotes the reaction [[Lipopolysaccharides co-treated with IFNG protein co-treated with TNF protein] results in increased expression of SOD2 protein] | PMID:16366677 PMID:26283207 PMID:33733559 | Ifng | affects expression | ISO | Ifng (Mus musculus) | 6480464 | CTD | resveratrol affects the expression of IFNG protein | PMID:20730501 | Ifng | decreases expression | ISO | IFNG (Homo sapiens) | 6480464 | CTD | resveratrol results in decreased expression of IFNG mRNA | PMID:21371465 | Ifng | decreases expression | ISO | Ifng (Mus musculus) | 6480464 | CTD | resveratrol results in decreased expression of IFNG mRNA; resveratrol results in decreased expression of IFNG protein | PMID:16256029 PMID:17872969 PMID:21340626 PMID:21807089 PMID:21937650 PMID:24073240 | Ifng | increases expression | ISO | Ifng (Mus musculus) | 6480464 | CTD | Resveratrol results in increased expression of IFNG mRNA | PMID:30165701 | Ifng | multiple interactions | ISO | IFNG (Homo sapiens) | 6480464 | CTD | [Benzo(a)pyrene co-treated with Resveratrol] results in decreased expression of IFNG protein; [IFNG protein results in increased expression of and results in increased localization of FAS protein] which results in increased susceptibility to Resveratrol; [IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with Resveratrol] results in increased activity of NFE2L2 protein; [IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with Resveratrol] results in increased expression of GCLC mRNA; [IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with Resveratrol] results in increased expression of HMOX1 mRNA; KHSRP protein promotes the reaction [Resveratrol inhibits the reaction [[IFNG protein co-treated with IL1B protein co-treated with TNF protein] results in increased expression of CXCL8 mRNA]]; KHSRP protein promotes the reaction [Resveratrol inhibits the reaction [[IFNG protein co-treated with IL1B protein co-treated with TNF protein] results in increased expression of NOS2 mRNA]]; KHSRP protein promotes the reaction [Resveratrol inhibits the reaction [[IFNG protein co-treated with IL1B protein co-treated with TNF protein] results in increased expression of TNF mRNA]]; Mesalamine inhibits the reaction [[IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with Resveratrol] results in increased expression of HMOX1 mRNA]; Resveratrol inhibits the reaction [[IFNG protein co-treated with IL1B protein co-treated with TNF protein] results in increased expression of CXCL8 mRNA]; Resveratrol inhibits the reaction [[IFNG protein co-treated with IL1B protein co-treated with TNF protein] results in increased expression of NOS2 mRNA]; Resveratrol inhibits the reaction [[IFNG protein co-treated with IL1B protein co-treated with TNF protein] results in increased expression of NOS2 protein]; Resveratrol inhibits the reaction [[IFNG protein co-treated with IL1B protein co-treated with TNF protein] results in increased expression of TNF mRNA]; Resveratrol inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased abundance of Nitric Oxide]; Resveratrol inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of CXCL8 mRNA]; Resveratrol inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of CXCL8 protein]; Resveratrol inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of PTGES2 protein]; Resveratrol inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of TNF mRNA]; Resveratrol inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of TNF protein]; Resveratrol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG protein]; Resveratrol inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of NOS2 protein]; Resveratrol inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of PTGS2 protein]; Resveratrol inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of MAPK1 protein]; Resveratrol inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of MAPK3 protein]; Resveratrol inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of RELA protein]; Resveratrol inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased secretion of CXCL10 protein]; Resveratrol inhibits the reaction [Lipopolysaccharides results in increased expression of IFNG protein]; Resveratrol inhibits the reaction [Oxygen deficiency results in increased expression of IFNG mRNA]; Resveratrol promotes the reaction [[IL1A protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of GCLM mRNA]; Resveratrol promotes the reaction [[TNF protein co-treated with IFNG protein] results in increased secretion of CXCL8 protein] | PMID:15779068 PMID:16154495 PMID:19549798 PMID:19561642 PMID:21756928 PMID:22698256 PMID:23452621 PMID:24289642 PMID:24707119 PMID:25352548 PMID:27818126 | Ifng | multiple interactions | ISO | Ifng (Mus musculus) | 6480464 | CTD | [Resveratrol co-treated with Tetracyclines] inhibits the reaction [Paraquat results in increased expression of IFNG protein]; KHSRP gene mutant form inhibits the reaction [Resveratrol inhibits the reaction [[IFNG protein co-treated with Lipopolysaccharides] results in increased expression of CXCL1 mRNA]]; KHSRP gene mutant form inhibits the reaction [Resveratrol inhibits the reaction [[IFNG protein co-treated with Lipopolysaccharides] results in increased expression of NOS2 mRNA]]; KHSRP gene mutant form inhibits the reaction [Resveratrol inhibits the reaction [[IFNG protein co-treated with Lipopolysaccharides] results in increased expression of TNF mRNA]]; Resveratrol affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of and results in increased secretion of IFNG protein]; Resveratrol inhibits the reaction [[[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of NOS2 mRNA] which results in increased chemical synthesis of Nitric Oxide]; Resveratrol inhibits the reaction [[IFNG protein co-treated with Lipopolysaccharides] results in increased expression of CXCL1 mRNA]; Resveratrol inhibits the reaction [[IFNG protein co-treated with Lipopolysaccharides] results in increased expression of NOS2 mRNA]; Resveratrol inhibits the reaction [[IFNG protein co-treated with Lipopolysaccharides] results in increased expression of TNF mRNA]; Resveratrol inhibits the reaction [Dextran Sulfate results in increased expression of IFNG protein]; Resveratrol inhibits the reaction [Ethanol results in increased activity of IFNG protein]; Resveratrol inhibits the reaction [IFNG protein results in increased abundance of Dinoprostone]; Resveratrol inhibits the reaction [IFNG protein results in increased abundance of Nitric Oxide] | PMID:11020457 PMID:16716911 PMID:19940103 PMID:20424383 PMID:21086752 PMID:23942037 PMID:24548422 PMID:25352548 PMID:28090784 | | ||||||||||||||||||||||
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